The Museum of Science, Boston will prototype several exhibit elements to be included in the Charles River Gallery, a new 3,000-square-foot exhibition gallery atop the Charles River Dam that explores the connection between the science of the natural world and that of the engineered world. The exhibits will be fabricated using the concepts of universal design in an ongoing effort to make the museum's offerings available to the greatest number of people, regardless of age, background, and ability. Through a combination of surveys and observational studies, museum staff will evaluate the effectiveness of proposed gallery components and use the results to improve visitor experience and comprehension of the new exhibit themes. The prototyping activities will also allow the museum to investigate how cross-disciplinary studies enable better understanding of human interaction in complex environments.