This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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TEAM MEMBERS:
Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
Partnering with National Musical Arts, the Science Museum of Minnesota seeks to develop BioMusic, a 4,000 sq. ft. traveling exhibition that explores the origins of music in nature and the connections between music and sound of living things. This project is based on planning grant ESI-0211611 (The Music of Nature and the Nature of Music) awarded to NMA. The project is based on the emerging interdisciplinary research field of biomusic, which includes musicology plus aspects of neuroscience, biology, zoology, environmental science, physics, psychology, math and anthropology. The exhibit sections -- "Humanimal" Music; Natural Symphonies; Ancient Roots; Music, Body and Mind; and World of Music -- use both music and natural sound to explore biodiversity, cultural diversity, the physics of sound and the brain. BROADER IMPACT: The exhibition is expected to travel for at least six years, reaching some two million people in 18 communities. It is to be accompanied by a six-part radio series (Sweet Bird Classics) for young children. Because of the connection to music and many other areas of public interest, this exhibition has the potential to attract and engage new audiences to science museums and stimulate their interest in STEM.
WNET is producing "The Human Spark," a multimedia project that includes a four-part television series (4 x 60 min) for national primetime broadcast on PBS, innovative outreach partnerships with museums, an extensive Web site and outreach activities, including a Spanish-language version and companion book. Hosted by Alan Alda, "The Human Spark" will explore the intriguing questions: What makes us human? Can the human spark be found in the differences between us and our closest genetic relative -- the great apes? Is there some place or process unique to the human brain where the human spark resides? And if we can identify it, could we transfer it to machines? The programs will explore these questions through presenting cutting-edge research in a number of scientific disciplines including evolution, genetics, cognitive neuroscience, behavioral science, anthropology, linguistics, AI, robotics and computing. The series will highlight opposing views within each field, and the interdisciplinary nature of science, including its intersection with the humanities. The series will develop a new innovative format, the "muse concept", which involves pairing the host with a different scientific expert throughout each program. The outreach plan is being developed with a consortium of four leading science museums, American Museum of Natural History in New York, Museum of Science in Boston, The Exploratorium in San Francisco, and the Fort Worth Museum of Science and History, paired with their respective local public television stations. An additional six museums and local broadcasters will be chosen through an RFP process to develop local initiatives around the series. Multimedia Research and Leflein Associates will conduct formative as well as summative evaluations of the series and web.
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TEAM MEMBERS:
William GrantJared LipworthGraham CheddBarbara Flagg
SoundVision Productions is developing and distributing a series of ten, hour-long public radio documentaries that will explore the turbulent boundary between science and the humanities, capturing the present moment of tremendous scientific and scholarly ferment with the unique and intimate power of radio. By introducing the radio audience to the thoughts and voices of some of the world\'s most accomplished scientists, in conversations with the counterparts in the humanities, the series will look at recent developments in science including physics, molecular and cell biology, environmental science, cognitive psychology and neuroscience, and the multiple disciplines of the life sciences reflecting the increasingly subtle and widespread application of evolutionary theory. In each program, a careful account of new scientific ideas and discoveries will be placed within the context of historical and contemporary thought about the human and natural worlds. Barinetta Scott, the Executive Producer, has most recently been the Executive Producer for the highly regarded NSF funded NPR series, "The DNA Files." In developing this project, she will work closely with an advisory committee that includes: John Avise, Research Professor, Dept. of Genetics, University of Georgia Samuel Barondes, Professor and Director of the University of California San Francisco\'s Center for Neurobiology and Psychiatry Terrence Deacon, Associate Professor of Anthropology, Boston University Anne Foerst, Professor of Computer Science and Theology, St. Bonaventure University Ursula Goodenough, Dept. of Biology, Washington University, St. Louis William Irons, Professor of Anthropology, Northwestern University Gordon Kane, Professor of Physics, University of Michigan Jim Miller, Senior Program Associate for the AAAS Program of Dialogue Between Science and Religion W. Mark Richardson, Episcopal Priest, Associate Professor of Systematic Theology, General Theological Seminary Holmes Rolston, University Distinguished Professor in the Department of Philosophy, Colorado State University Michael Ruse, Professor of the Philosophy of Biology and Ethics, at Florida State University Mary Evelyn Tucker, Professor of Religion at Bucknell University Dorothy Wertz, Senior Scientist; Social Science, Ethics, and the Law; The Shriver Center.
The National Research Council, through its Board on Science Education, will carry out a synthesis study of informal science learning based on a workshop funded by a prior NSF planning grant. The intellectual merit of this project is based on the formation of a committee of experts representative of the diversity of the field who will engage in a fact-finding process on learning science in informal settings, deliberate about the evidence and produce a major report that will be published by the National Academies Press. The study will describe the status of knowledge in the field currently, articulate a common framework for the next generation of research on informal science learning and provide guidance to the community of practice. By presenting what we know about the characteristics of effective informal science learning environments across a range of outcome measures, the study will achieve broader impacts by assisting practitioners, policymakers and researchers in directing their efforts towards realizing the potential of informal science education for advancing public science literacy.
Maine is a rural state with unequal access to computers and information technology. To remedy this, the Maine laptop program supplies iBooks to every seventh and eighth grade student in the state. The goal of EcoScienceWorks is to build on this program and develop, test and disseminate a middle school curriculum featuring computer modeling, simple programming and analysis of GIS data coupled with hands-on field experiences in ecology. The project will develop software, EcoBeaker: Maine Explorer, to stimulate student exploration of information technology by introducing teachers and students to simple computer modeling, applications of simulations in teaching and in science, and GIS data manipulation. This is a three-year, comprehensive project for 25 seventh and eighth grade teachers and their students. Teachers will receive 120 contact hours per year through workshops, summer sessions and classroom visits from environmental scientists. The teachers' classes will field test the EcoScienceWorks curriculum each year. The field tested project will be distributed throughout the Maine laptop program impacting 150 science teachers and 17,000 middle school students. EcoScienceWorks will provide middle school students with an understanding of how IT skills and tools can be used to identify, investigate and model possible solutions to scientific problems. EcoScienceWorks aligns with state and national science learning standards and integrates into the existing middle school ecology curriculum. An outcome of this project will be the spread of a field tested IT curriculum and EcoBeaker: Maine Explorer throughout Maine, with adapted curriculum and software available nationally.
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TEAM MEMBERS:
Walter AllanEric KlopferEleanor Steinberg
Independent Production Fund is producing a three-part public television series focusing on the latest research in the science of music. The programs will explore how cutting-edge science is revealing new connections between music and the human mind and body, the natural world and the cosmos. The series will follow researchers from a variety of fields including physiology, neuroscience, psychology, biology, physics and education, as they use groundbreaking techniques and technologies to unravel age-old mysteries about music's persistence, universality and emotional power. It will show how these researchers are shedding valuable new light on the way brains work. The impact of the programs will be extended through a content-rich companion web site and innovative formal and informal educational-outreach materials to both middle and high school age students, as well as a complementary radio component. Mannes Productions will produce the series; Goodman Research Group will conduct formative evaluation and Rockman et al will conduct summative evaluation.
Kikim Media requests $743,316 to produce four half-hour television documentaries and associated outreach programs based on Michael Pollan's best-selling book, The Botany of Desire. The project explores the reciprocal nature of people's relationship with plants. The programs focus on the connections between apples and the human desire for sweetness; tulips and the desire for beauty; marijuana and the desire for intoxication; and corn and our desire for control over nature. The project will increase public understanding of diverse subjects including genetics, evolution, cognition and biochemistry as well as biodiversity, genetic diversity and the consequences of their loss. The project will have a broad impact through a national primetime PBS broadcast, an outreach program targeting adult audiences, and an educational module delivering appropriate content (excluding intoxication) to middle and high school audiences. Knight-Williams Research Communications will conduct the evaluation for The Botany of Desire television broadcast and outreach efforts.
The Wildlife Conservation Society (WCS), the umbrella organization including the Bronx Zoo, will design, develop, fabricate, evaluate and install a long-term exhibition with ancillary public programming about the biology and conservation science of the island of Madagascar. Based in part on long-term scientific research conducted in Madagascar by the WCS, the exhibit will use immersive, interactive exhibit approaches including live plants and animals, as well as an on-line curriculum (Wild Explorations in Science), distance learning expeditions, and an interactive website to engage visitors of all ages in experiencing conservation science and specific examples of science saving wildlife. Visitors will explore unique and beautifully re-created habitats, encounter fascinating animals and learn about concepts such as endemism, island biogeography and biodiversity. The exhibit will serve about 2,000,000 visitors to the Bronx Zoo annually and millions nationwide through on-line curricula and distance learning programs.
This project is designed to improve communication between scientists and the public focusing on the role of evidence in science. It is a two-year project that includes: 1) implementing a national survey on the public use of science web sites; 2) conducting a national Science Education Outreach Forum bringing together scientists and informal science educators; 3) implementing workshop sessions at a national conference to disseminate lessons learned from the survey and Forum; and 4) developing a prototype website on the role of evidence that will be evaluated for audience engagement and understanding. This project builds on the Exploratorium's prior NSF-funded project (ESI#9980619) developing innovative strategies using the Internet to link scientists and the public using Webcasts, annotated datasets and interactive web resources. Project collaborators include the Pew Internet and American Life Project, Palmer Station, Scripps Oceanographic Institute, FermiLab and the Society of Hispanic Physicists among others. The research and evaluation of the project has the potential for strategic impact by providing new information and models on how science centers can more effectively use the Internet to improve communication between scientists and the public while engaging learners more effectively.
This project is a multimedia initiative designed to increase the public and youth understanding of how scientists work. Deliverables include "Pulse of the Planet" radio programs in both English and Spanish; related web news features and photo galleries at National Geographic.com; and formative and summative evaluations of the project. The project will select 27 scientists and citizen scientists (7 of them Latinos) to provide first-person "insider" stories of scientific endeavor using the "audio diary" format. They will be provided with minidisk field recording kits and digital cameras and given hands-on training by the PI. Excerpts from their diaries will be used on the nationally broadcast radio programs and website. Some of these will feature citizen science projects. The project's partners include The Self-Reliance Foundation and the Hispanic Radio Network that will produce Spanish-language adaptations of Pulse of the Planet programs; the National Geographic will create editorial features for its news website; and Citizen Science project partners including Cornell's Lab of Ornithology, and Earthwatch, among others will encourage direct participation in projects linked to the radio and web information. It is estimated that 1.25 million people will hear each of the radio programs and 50,000 unique visitors will read the stories on the web site.
The Science Museum of Minnesota (SMM) will develop "Water Planet," a 5,000 square foot traveling exhibit, web site, and associated programs focusing on the new and evolving field of Earth system science. It will apply the dynamic technologies of "Science-on-a-Sphere," " Digital River Basin," and "GEO-Wall II" to engage museum visitors in the processes by which water mediates many interactions among the atmosphere, hydrosphere, cryoshpere, biosphere and geosphere. Through these techniques, it will explore the potential of using large satellite and ground-based datasets, computermodeling, simulations and visualizations to increase public understanding of Earth system research. Scientific collaborators include the National Center for Earth System Dynamics (Universiy of Minnesota, Twin Cities); Center for Advanced Materials for Purifiction of Water with Systems (University of Illinois, Champaign-Urbana); and Sustainability of Semi-Arid Hydrology and Riparian Areas (University of Arizona, Tucson). BROADER IMPACTS: "Water Planet" will reach some three million people, with a focus on local water conservation and pollution issues and the way the entire planet functions. In addition, through collaboration with the University of Connecticut Nonpoint Education for Municipal Officers (NEMO) program, the exhibition will help educate local government officials at exhibition venues. SMM also will partner with the Fond du Lac Tribal and Community College Headwaters Science Center for educational outreach programs. These applications of scientific visualization technology and lessons from this project will be shared with the science museum at large through a web site created for this purpose and other forms of professional dissemination.
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TEAM MEMBERS:
Patrick HamiltonRoberta CooksDouglas JohnstonGary WoodardPaul Morin