This award is for a Science and Technology Center devoted to the emerging area of nanobiotechnology that involves a close synthesis of nano-microfabrication and biological systems. The Nanobiotechnology Center (NBTC) features a highly interdisciplinary, close collaboration between life scientists, physical scientists, and engineers from Cornell University, Princeton University, Oregon Health Sciences University, and Wadsworth Center of the New York State Health Department. The integrating vision of the NBTC is that nanobiotechnology will be the genesis of new insights into the function of biological systems, and lead to the design of new classes of nano- and microfabricated devices and systems. Biological systems present a particular challenge in that the diversity of materials and chemical systems for biological applications far exceeds those for silicon-based technology in the integrated-circuit industry. New fabrication processes appropriate for biological materials will require a substantial expansion in knowledge about the interface between organic and inorganic systems. The ability to structure materials and pattern surface chemistry at small dimensions ranging from the molecular to cellular scale are the fundamental technologies on which the research of the NBTC is based. Nanofabrication can also be used to form new analytical probes for interrogating biological systems with unprecedented spatial resolution and sensitivity. Three unifying technology platforms that foster advances in materials, processes, and tools underlie and support the research programs of the NBTC: Molecules of nanobiotechnology; Novel methods of patterning surfaces for attachment of molecules and cells to substrates; and Sensors and devices for nanobiotechnology. Newly developed fabrication capabilities will also be available through the extensive resources of the Cornell Nanofabrication Facility, a site of the NSF National Nanofabrication Users Network. The NBTC will be an integrated part of the educational missions of the participating institutions. NBTC faculty will develop a new cornerstone graduate course in nanobiotechnology featuring nanofabrication with an emphasis on biological applications. Graduate students who enter the NBTC from a background in engineering or biology will cross-train in the other field by engaging in a significant level of complementary course work. Participation in the NBTC will prepare them with the disciplinary depth and cross-disciplinary understanding to become next generation leaders in this emerging field. An undergraduate research experience program with a strong mentoring structure will be established, with emphasis on recruiting women and underrepresented minorities into the program. Educational outreach activities are planned to stimulate the interest of students of all ages. One such activity partnered with the Science center in Ithaca is a traveling exhibition for museum showings on the subject of nano scale size. National and federal laboratories and industrial and other partners will participate in various aspects of the NBTC such as by hosting interns, attendance at symposia and scientist exchanges. Partnering with the industrial affiliates will be emphasized to enhance knowledge transfer and student and postdoctoral training. This specific STC award is managed by the Directorate for Engineering in coordination with the Directorates for Biological Sciences, Mathematical and Physical Sciences, and Education and Human Resources.
The Science Museum of Minnesota will develop "Investigations in Cell Biology," an integrated program that introduces cell, microbiology, and molecular biology to museum audiences through open-access, wet-lab, micro-experiment benches; training and support for school teachers; classes for adults and teens; and a long-term program for local high school youth. The project includes the development, testing, and installation of four micro-experiment benches that introduce visitors to the objectives, tools, and techniques of cell biology experimentation. These benches,"Inside the Cell," "Testing for DNA," "DNA Profile," and "Microbe Control," will be part of "Cell Lab," a 1,500 square-foot open experiment area within the science museum's new core exhibition, "The Human Body," opening December 1999.
DATE:
-
TEAM MEMBERS:
Laurie Kleinbaum FinkSusan FlemingJ Newlin
The North Carolina Museum of Life and Science will develop two areas in a new 70 acre outdoor exhibit "BioQuest Woods: Linking Animals and Plans with Interactive Exhibits". This concept is to pair live animals and plants in their natural setting with science center-style interactive exhibits to communicate key ideas in biology and physics. Support will go to sixteen interactive stations in two four-acre theme areas "Catch the Wind" and "Down to Earth". "Catch the Wind" will assist visitors in the exploration air movement and learning about how plants and animals use air in specialized ways. For example, visitors will experiment with air thermals while observing the behavior of birds of prey and will learn how prairie dogs exploit the venturi effect to ventilate their burrows. In the "Down to Earth" thematic area, visitors, simulate the activities of field biologists, will track bears equipped with radio collars, examine living invertebrates, among other activities. Scientific instruments, including microscopes, in kiosks will aid on-the-scene study of live animals and plans. "BioQuest Woods" will help visitors, teachers and students gain the realistic experience of scientific inquiry in a natural setting. Education programming will highlight curriculum linkages and fulfills the goals of North Carolina's new science curriculum. It directly addresses the State's competency-based goals requiring understanding of natural systems and the interrelations of the basic sciences. Pre and post-visit materials will be developed along with teacher guides and enhancement activities. This project is being developed with the cooperation of the Austin Nature Center, the National Zoo, and the Indianapolis Zoo.
The Ft. Worth Museum of Science and History will develop "Texas Dinosaurs: How Do We Know? -- Regional Dissemination of Science Inquiry Exhibits and Educational Programs on Paleontology." This will be a major permanent and portable exhibition project that will be accompanied by an array of educational programs for formal and informal audiences throughout Texas. The permanent 12,000 sq. ft. exhibit, "Texas Dinosaurs: How Do We Know?", will recreate field and laboratory processes of paleontological research in an inquiry approach to public learning in geology, biology, ecology and mathematics. Portable versions of the exhibit will be distributed to the Dinosaur Valley State Park in Glen Rose, the Texas Parks and Wildlife Headquarters, the Panhandle-Plains Historical Museum in Canyon, the Science Spectrum in Lubbock, the McAllen International Museum, and the El Paso Insights Science Museum -- all in Texas. Regional dissemination of "How Do We Know?" exhibits and educational programs and materials will reach at least 1.5 million people annually, including isolated rural communities in the large geographic region of Texas.