Phylogenetic groupings of organisms are the basis for predictive classifications and biological information systems. Organizing biological knowledge and their parallel hierarchies according to phylogenetic relationships has become increasingly important for many segments of science and society (i.e., genetic databases such as GenBank). Yet, our understanding of the tree of life is still very incomplete at all taxonomic levels because phylogenetic hypotheses are typically characterized by inadequate taxon samples, and the data themselves are often variable across the included taxa with respect to kind, quantity, and quality. In addition, methods of analysis vary in their appropriateness and applicability, thus making comparison of phylogenetic trees difficult. These impediments need to be addressed if we are to have a tree of life for the major groups of organisms within a reasonable time frame. Equally important will be to ensure that phylogenetic knowledge is accessible and useful to researchers, institutions, and the government agencies who need it. This proposal seeks to bring together approximately 25-30 leading systematic biologists and nonsystematists interested in phylogenetic research and informatics (phyloinformatics). The workshop will attempt to identify the research needed to assemble the tree of life and make that information available to the global user community within a reasonable time frame. The workshop will formulate recommendations designed to promote institutional changes within the systematic research community to accelerate phylogenetic understanding, identify research efforts that will result in large-scale increases in phylogenetically informative data and improve data analysis, and specify research, technological advances, and infrastructural needs to store, retrieve, and manipulate large amounts of phylogenetic information and make it widely available.
The Milwaukee Public Museum will develop Adventures in Science: An Interactive Exhibit Gallery. This will be a 7250 sq. ft. interactive exhibit with associated public programs and materials that link the exhibit with formal education. The goal of Adventures in Science is to promote understanding of biological diversity, the forces that have change it over time, and how scientists study and affect change. The exhibit will consist of three areas. "Our Ever-Changing World" will feature "dual scene" habitat dioramas that will convey at-a-glance how environments change over time. "The Natural History Museum" will be a reconstruction of a museum laboratory and collections area to protray behind-the-scenes scientific and curatorial activities that further the study of biological diversity, ecology and systematics. An "Exploration Center: will bridge these two areas and will be designed to accommodate live presentations, group activities and additional multimedia stations for Internet and intranet access. Using interactive devices, visitors will be encouraged to make hypothesis, examine evidence, compare specimens, construction histories of biological and geological changes, and develop conclusions about the science behind biodiversity and extinction issues. Visitors should also come away with an increased understanding of the role of systematic collections in understanding biological diversity. Information on MPM research programs will be highlighted in "The Natural History Museum" section and will be updated frequently. Annual Teacher Training Institutes for pre-service and in-service teachers will present strategies for using the gallery's multimedia stations, lab areas, and Web site links. Special attention will be given to reaching new audiences including those in the inner city and people with disabilities.
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TEAM MEMBERS:
Allen YoungJames KellyPeter SheehanSusan-Sullivan BorkinRolf JohnsonMary Korenic
resourceprojectProfessional Development, Conferences, and Networks
This model science teacher retention and mentoring project will involve more than 300 elementary teachers in "Lesson Study" of inquiry science around school gardens. Drawing on the rich resources of the University of California Botanical Garden and the science educators at the Lawrence Hall of Science this project will develop Teacher Leaders and provide science content professional development to colleagues in four urban school districts. Using the rich and authentic contexts of gardens to engage students and teachers in scientific inquiry opens the opportunity to invite parents to become actively involved with their children in the learning process. As teachers improve their classroom practices of teaching science through inquiry with the help of school-based mentoring they are able to connect the teaching of science to mathematics and literacy and will be able to apply the lesson study approach in their teaching of other innovative projects. Teacher leaders and mentors will have on-going learning opportunities as well as engage participating teachers in lesson study and reflection aimed toward improving science content understanding and the quality of science learning in summer garden learning experiences and having context rich science inquiry experiences throughout the school year.
This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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TEAM MEMBERS:
Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
The National Center for Earth-surface Dynamics (NCED) is a Science and Technology Center focused on understanding the processes that shape the Earth's surface, and on communicating that understanding with a broad range of stakeholders. NCED's work will support a larger, community-based effort to develop a suite of quantitative models of the Earth's surface: a Community Sediment Model (CSM). Results of the NCED-CSM collaboration will be used for both short-term prediction of surface response to natural and anthropogenic change and long-term interpretation of how past conditions are recorded in landscapes and sedimentary strata. This will in turn help solve pressing societal problems such as estimation and mitigation of landscape-related risk; responsible management of landscape resources including forests, agricultural, and recreational areas; forecasting landscape response to possible climatic and other changes; and wise development of resources like groundwater and hydrocarbons that are hosted in buried sediments. NCED education and knowledge transfer programs include exhibits and educational programs at the Science Museum of Minnesota, internships and programs for students from tribal colleges and other underrepresented populations, and research opportunities for participants from outside core NCED institutions. The Earth's surface is the dynamic interface among the lithosphere, hydrosphere, biosphere, and atmosphere. It is intimately interwoven with the life that inhabits it. Surface processes span environments ranging from high mountains to the deep ocean and time scales from fractions of a second to millions of years. Because of this range in forms, processes, and scales, the study of surface dynamics has involved many disciplines and approaches. A major goal of NCED is to foster the development of a unified, quantitative science of Earth-surface dynamics that combines efforts in geomorphology, civil engineering, biology, sedimentary geology, oceanography, and geophysics. Our research program has four major themes: (1) landscape evolution, (2) basin evolution, (3) biological sediment dynamics, and (4) integration of morphodynamic processes across environments and scales. Each theme area provides opportunities for exchange of information and ideas with a wide range of stakeholders, including teachers and learners at all levels; researchers, managers, and policy makers in both the commercial and public sectors; and the general public.
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TEAM MEMBERS:
Efi Foufoula-GeorgiouChristopher PaolaGary Parker
The Parents Involved/Pigeons Everywhere (PIPE) project is a collaboration between KCTE-Community Television of Southern California, The American Association for the Advancement of Science, and the Cornell Laboratory of Ornithology. They are developing a three-year model project to engage parents in science education with their children through Project PigeonWatch, a citizen-science program run by Cornell University. The PIPE project will develop videos and written materials for use in a series of parent workshops designed for libraries and community science centers. The materials and workshops will be targeted to low-income parents with children in grades three through five and will be tested at 27 pilot sites around the country. A PIPE leader's Web Site will link all of the pilot sites. At the end of the pilot stage, the video and print materials will be widely available and the applicants will produce a publication that indicates strategies for using and building on PIPE and will provide assistance to new sites that wish to implement the program.
The Science Museum of Minnesota will develop "Investigations in Cell Biology," an integrated program that introduces cell, microbiology, and molecular biology to museum audiences through open-access, wet-lab, micro-experiment benches; training and support for school teachers; classes for adults and teens; and a long-term program for local high school youth. The project includes the development, testing, and installation of four micro-experiment benches that introduce visitors to the objectives, tools, and techniques of cell biology experimentation. These benches,"Inside the Cell," "Testing for DNA," "DNA Profile," and "Microbe Control," will be part of "Cell Lab," a 1,500 square-foot open experiment area within the science museum's new core exhibition, "The Human Body," opening December 1999.
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TEAM MEMBERS:
Laurie Kleinbaum FinkSusan FlemingJ Newlin
Two 8 to 10 week modules, one focusing on cells and the other on reproduction and heredity, serve as the basis for the development of a comprehensive, assessment-driven, middle school science curriculum called "Science for Today and Tomorrow." A curriculum frramework is developed for Life and Physical Sciences to be taught in Grades 6 and 7 and Earth Science in Grade 8. The research-based materials assist students to develop a working knowledge of a core set of ideas that are fundamental to the discipline and ultimately to see how the concepts span the disciplines. The student materials and the teachers' guides are enhanced with classroom-tested assessments and web-based content resources, simulations and tools for gathering and interpreting data. On-line professional development materials allow teachers to gain content knowledge and pedagogical skills. The website also contains an area that provides information for administrators including strategies for supporting teachers and another area for community members to involve them in the students' science learning. The project builds upon the lessons learned in previous materials development projects at TERC.
The Bay Area Discovery Museum will expand their "My Place by the Bay" theme with new programmatic elements that "reinforce the theme that people, plants and animals live together and depend upon each other to survive." Three new activity areas will be developed that focus on science learning: A) an outdoor "Tot Lot" for early science learners; B) an outdoor "Discovery Cove" focusing on place-specific elements of their bayshore site; and C) an indoor recreated "Research Vessel" outfitted with a simulated navigaion station and marine biology laboratory. The learning goals for these three areas are: 1) "The Bay environment is home to many living things"; and 2) "I can do science to explore and learn about my world". The "Tot Lot," built into a hill, will be a one-half acre, multi-sensory, outdoor, prepared environment for children under five to learn about animals living in three distinct Bay habitats: woodland, stream and meadow. The "Discovery Cove" will be a two-acre area prepared environment for children up to age eight. Learners will be encouraged to see the bay as an integrated system that includes animal adaptations, ecological relationships and human activity. The "Research Vessel" is inspired by the R/V Questuary and is the place where visitors will use authentic tools to do science. Other features of this project include an integrated system of Parenting Messages that includes special signage for parents and a Families Ask Guide for families with children ages seven and under that is a joint effort of DABM, Golden Gate National Recreation Area and the Golden Gate National Parks Association. They will also develop a series of teacher workshops that will link this informal learning space with the needs of formal education. One specific school group with whom they will work is the Junipero Serra, an NSF Urban Systemic Intiative site.
Massachusetts General Hospital, representing Partners HealthCare System, Inc., is producing a large format film on the brain that is designed to increase the popular understanding of brain biology and recent advances in neuroscience. Framed within the larger question of the unique abilities of the human mind, the project will take an interdisciplinary look at brain science and raise questions about the nature and biological basis of diverse aspects of human experience including consciousness. By following a rider in the Tour de France, the film will illustrate how the brain functions in both normal and stressful situations. Major sequences will explore vision, memory and emotion. Slightly shorter sequences will delve into imagination and creativity, language, dreams and pain. Brief "interludes" will allow the film to reflect on the brain as it is represented in a range of human capabilities. Finally, the film turns it attention to consciousness, self-awareness and the totality of experiencing life as a human. Outreach components of the project include: A weeklong national symposium for museum educators, teachers, and community organizations from all regions of the country. Follow up regional "Brain Workshops" designed to provide more focused project support. "The Brain: Exploratory Trips Into the Final Frontier" -- An Educator/Student Activity Guide Fun Facts Family Guide to "The Brain" An Educational Lobby Kiosk "Head Trip: A Voyage Through the Young Human Mind" -- An illustrated instructional brochure A Brain Website The film will be directed by Bayley Silleck whose prior large format films include "Cosmic Voyage" and "Lost Worlds: Life in the Balance." The lead scientific advisors are Dr. Dennis Selkow, Professor of Neurology and Neuroscience at Harvard Medical School, and Dr. Anne Young, Julieanne Dorn Professor of Neurology at Harvard Medical School. There also will be a seven-member advisory committee composed of neuroscientists, psychologists and philosophers.
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TEAM MEMBERS:
JoAnna Baldwin-Mallory
resourceprojectProfessional Development, Conferences, and Networks
The Exploratorium will create the "Outdoor Exploratorium," a 10,000-square-foot, open-air exhibit environment comprising 20 to 25 original installations. Each exhibit will allow visitors to interact directly with a variety of elements, that is water, wind, sound, light, and living things, as they exist in the natural world. One of the key components of this project will be the use of "Noticing Tours." Led by staff scientists, artists, educators, exhibit developers, and other "expert noticers," the tours will initiate a dialogue with the visitors as a starting point for exhibit development. To augment visitor learning and unify the museum's entire collection, exhibit text will relate the "Outdoor Exploratorium" experiences to exhibits. The project will culminate in a workbook for the field and two workshops for museum professionals. The Exploratorium Teacher Institute staff will develop two-week institutes that make extensive use of the "Outdoor Exploratorium." Classroom activities and inquiry-based learning experiences will be developed based on the new exhibits.
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TEAM MEMBERS:
Peter RichardsThomas HumphreyThomas RockwellTheodore KoterwasJoyce Ma
The Natural History of Museum of Los Angeles County will mount and administer a five (5) year tour of an exhibition, "Dogs: Our Canine Companions," which explores the evolution, behavior, diversity and cultural significance of dogs. Visitors to the 6,000 sq. ft. exhibit will gain a better knowledge of these familiar animals through a variety of componenets including hands-on displays, videos, graphic panels, computer-generated images, dioramas, fossil skeletons and educational curriculum materials. The exhibit will be divided into eight (8) sections. Throughout the sections there are recurring themes to unify the educational messages of the adaptive diversity of canids, the relationship between wild and domestic dogs, and the relationship between dogs and humans -- especially service dogs. The dissemination of DOGS will include presentations to groups and conferences, with particular emphasis on the exhibit's treatment of accessibility issues. There will be an extensive web site with animation, movies, sound and interactive elements to further enhance the effectiveness of the exhibit and the availability of educational materials. the final ancillary materials to accompany the traveling exhibition will be a theater production, a free-standing, self-contained learning center, an exhibit guide, and a CD-Rom. Formal education providers will benefit from workshops, curriculum guides, and teaching kits.
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TEAM MEMBERS:
Linda AbrahamBlaire Van ValkenburghRobert Wayne