This award is for a Science and Technology Center devoted to the emerging area of nanobiotechnology that involves a close synthesis of nano-microfabrication and biological systems. The Nanobiotechnology Center (NBTC) features a highly interdisciplinary, close collaboration between life scientists, physical scientists, and engineers from Cornell University, Princeton University, Oregon Health Sciences University, and Wadsworth Center of the New York State Health Department. The integrating vision of the NBTC is that nanobiotechnology will be the genesis of new insights into the function of biological systems, and lead to the design of new classes of nano- and microfabricated devices and systems. Biological systems present a particular challenge in that the diversity of materials and chemical systems for biological applications far exceeds those for silicon-based technology in the integrated-circuit industry. New fabrication processes appropriate for biological materials will require a substantial expansion in knowledge about the interface between organic and inorganic systems. The ability to structure materials and pattern surface chemistry at small dimensions ranging from the molecular to cellular scale are the fundamental technologies on which the research of the NBTC is based. Nanofabrication can also be used to form new analytical probes for interrogating biological systems with unprecedented spatial resolution and sensitivity. Three unifying technology platforms that foster advances in materials, processes, and tools underlie and support the research programs of the NBTC: Molecules of nanobiotechnology; Novel methods of patterning surfaces for attachment of molecules and cells to substrates; and Sensors and devices for nanobiotechnology. Newly developed fabrication capabilities will also be available through the extensive resources of the Cornell Nanofabrication Facility, a site of the NSF National Nanofabrication Users Network. The NBTC will be an integrated part of the educational missions of the participating institutions. NBTC faculty will develop a new cornerstone graduate course in nanobiotechnology featuring nanofabrication with an emphasis on biological applications. Graduate students who enter the NBTC from a background in engineering or biology will cross-train in the other field by engaging in a significant level of complementary course work. Participation in the NBTC will prepare them with the disciplinary depth and cross-disciplinary understanding to become next generation leaders in this emerging field. An undergraduate research experience program with a strong mentoring structure will be established, with emphasis on recruiting women and underrepresented minorities into the program. Educational outreach activities are planned to stimulate the interest of students of all ages. One such activity partnered with the Science center in Ithaca is a traveling exhibition for museum showings on the subject of nano scale size. National and federal laboratories and industrial and other partners will participate in various aspects of the NBTC such as by hosting interns, attendance at symposia and scientist exchanges. Partnering with the industrial affiliates will be emphasized to enhance knowledge transfer and student and postdoctoral training. This specific STC award is managed by the Directorate for Engineering in coordination with the Directorates for Biological Sciences, Mathematical and Physical Sciences, and Education and Human Resources.
The Exploratorium will develop a 6000 sq. f.t exhibit Seeing: The Interaction of Physiology, Culture, and Technology . As the first exhibit and program development project of their multiyear initiative "Refocusing on the Floor," this permanent exhibit will consist of approximately 60 new and redesigned exhibits organized into six sections: Seeing Central, Light and Images, Process of Seeing, Seeing Things Differently, Extending Our Vision, and Deconstructing What We See. Visitors will develop their skills at seeing, noticing, and visual thinking, will become more conscious of visual information in daily life, be exposed to current research on vision and visual cognition, be given opportunities to investigate the social and cultural influences on seeing, and be lead to the realization that seeing, interpreting, and understanding visual information are basic to the conduct of science. New partnerships will be developed with community-based organizations that will promote new audiences for the Exploratorium as well as enhance the viewpoints of the participating staff members. The activities will address the National Science Standards in terms of the process skills that are identified and will reintroduce visual thinking skills into the activities linking the exhibit with the formal education's curriculum. Additional workshops and professional dissemination activities will be included in the overall project.
The Museum of Science and Industry will develop "Genetics: Decoding Life," a 4325 sq. ft. permanent exhibit about the basic principles of genetics, the Human Genome Project, new tools and technology to study life, and the biomedical and biotech applications resulting from genetic information. As a result of interacting with this exhibit, visitors will understand the basic principles of genetics, they will become familiar with the role of genes in the development of life, they will learn something about how and why scientists used genetic tools, and visitors will become aware of applications of these principles and the potential social, ethical, medical and economic outcomes. In addition to the exhibit there will be a number of complementary outreach programs. An electronic web site will be created, software used in the exhibit will be modified into a format suitable for use in schools, computers loaded with genetic programs will be loaned to Chicago public school groups, churches and other community agencies, and the content of the exhibit will be used to enhance special Lamaze and prenatal classes held at the museum. Special consideration will be given to developing the relationship between the project personnel and the staff of the Chicago Systemic Initiative. They will work together to produce a school program about genetics that will be suitable for grades 5 to 8. School materials will include a teacher's guide for the exhibit, a program of classroom activities, and materials to be used before and after a trip to the museum to see the exhibit.
David Grubin Production, Inc., in conjunction with Thirteen/WNET, is producing a multimedia project entitled, The Secret Life of the Brain. The project will examine new understandings into the processes of the human brain that have developed over the last decade. Through an exploration of the brain's normal development from conception through old age, the project conveys the most recent knowledge available. The series will enable audiences to appreciate the current revolution in neuroscience, understand how new technologies have enabled scientists to unearth a wealth of information, and learn how neuroscience research impacts the health and future well-being of the average person. The five one-hour programs in the series will explore the brain from conception through age two, childhood from age two through puberty, adolescence, adulthood, and normal aging process in older age. Educational outreach materials for use in informal and formal setting will include two separate sets of printed materials, one for adolescents and one for adults. A Secret Life of the Brain Web Site will include Brain Games, the Brain Quiz, and the Live Brain that present learning opportunities for adults and teens. The project Principal Investigator will be David Grubin who will serve as Executive Producer. Grubin previously was the producer of Healing and the Mind with Bill Moyers and the critically acclaimed biographies of Lyndon Johnson, Franklin Roosevelt, and Theodore Roosevelt. June Kinoshita, an internationally recognized science reporter and editor, will serve as the Series Science Editor. Lead advisors for each program will be Bruce McEwen, President-elect of the Society for Neuroscience and Professor at Rockefeller University (Program 1); Steve Petersen, Director, Division of Neuropsychology, Dept. of Neurology and Neurological Surgery at the Washington University School of Medicine (Program 2); Steven Hyman, Director of the National Institute of Mental Health (Programs 3 & 4); and Carl Cotman, Director for the Institute for Brain Aging and Dementia at the University of California, Irvine (Program 5). Robert Miller of WNET will be responsible for the educational materials to accompany The Secret Life of the Brain.
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TEAM MEMBERS:
David GrubinTamara RobinsonWilliam Grant
A new, permanent exhibition at the San Diego Museum of Man will reflect the great scientific strides made in unraveling the mysteries of our uniquely human biology. The exhibit of 7,000 sq. ft. will take visitors on a 65-million year journey through time and even go beyond the present with glimpses of current technologies which will shape the future of human evolution. The exhibit development is being guided by a team of renowned scholars, museum professionals and community members in order to insure that the material is scientifically accurate, current and comprehensive. Evaluation and community input combined with engaging exhibitry will further enhance the informal science learner's experience. The exhibit will be about time, genetics and the environment. Dioramas, casts, artifacts and engaging interactives will convey the storyline. As a result of the development of culture, technology is refined and becomes intertwined with the human evolution. The exhibit will unify and draw together other halls in the museum. Further hands-on discovery will be encouraged in an outdoor archaeological site. Associated programming, which will foster the integration of research and education, will include a lecture series, on-line chats and guidebooks, as well as resources for teachers and students.
The Fred Friendly Seminars is producing a three-part, prime-time television series about the ethical, legal and social implications of advances in genetic research and technology. The audience for the series is the general public with special emphasis on the scientific and policy-making communities. Each of the programs will begin with a presentation of the basic genetic science linked to a specific ethical and policy issue and then will engage a panel in a Socratic dialogue based on a hypothetical situation related to that issue. The panel will represent a wide range of perspective including scientists, policy makers and people experiencing the dilemmas presenting in the hypothetical situations. Outreach material for the project will be developed by the National Center for Science Literacy, Education and Technology and Exhibition at the American Museum of Natural History. The center will produce a 16-page discussion guide designed for by a variety of informal education organizations that reach the general public. This guide will be available in both print and on the project web site. In addition to the guide, the web site include guidelines about how to use segments of the series as catalysts for discussion, a list of annotated resources on genetics, and a behind-the-scenes look at the genomic research labs of the museum.
The Informal Science Education Program has been supporting the radio series "Living on Earth" for several years. The World Media Foundation is now adding environmental science and technology features to "Living on Earth" and is developing and testing an outreach component that will involve youth as researchers and radio producers. The science and technology features, ranging in length from four to twenty-four minutes, will depart from the usual news-driven reports on the programs. Many of the segments will illustrate basic building blocks of environmental science, technology and related mathematics. Others will profile diverse pioneers in these disciplines. The radio programs will be the framework for an interdisciplinary exploration program for youth. Working with a team of educators from the Antioch University Graduate Program in Environmental Education, the project staff will develop a program in which secondary school aged youth cooperate with peers to produce professional, concise reporting on local environmental issues. Living on Earth will feature the best of the student work on National Public Radio and highlight these pieces as an expanded feature on its website.
SoundVision Productions is producing new programs for "The DNA Files." This highly regarded and very successful radio series is designed to further public understanding of genetic science as well as the ethical, legal and social issues emanating from genetics and biotechnology. These five, new, one-hour programs and feature segments will be on topics that have emerged in recent years as significant developments in the realm of genetic research such as pollution prevention and reduction and the patenting of gene sequences and related genetic information. Specific topics tentatively planned for the new programs include: "The Ecology of Genetic Engineering," "The Genetics of Memory and Aging," "The Genetics of X and the Genetics of WHY," and "Genetic Diseases of the Brain." The programs and features will also introduce those products and processes that, while currently viewed as only future fantasies of the biotech industry, are likely to become real in one or another within the lifetimes of the current generation of public radio listeners. The major outreach component of the project will be via a World Wide Web site. This is a particularly appropriate medium for outreach for this project since demographic studies indicate that most members of the public radio audience have computers and are able to access the web. SoundVision will upgrade the present "The DNA Files" web site to become a more active and integrated part of the project. Every program will have a dedicated section on the web site that will provide expended information and resources beyond those included in the broadcast. The web will provide a forum for public interaction with the issues by engaging the scientists, related experts, policy makers and the public. The project also will make cassette tapes and transcripts of the programs available on request. The PI is Bari Scott, who is the Executive Producer for the series; Jude Thilman will serve as Project Director. The programs are hosted by NBC Dateline reporter John Hockenberry and distributed by National Public Radio. Project advisors in the field of genetics include Elbert Branscomb, Luca Cavalli-Sforza, Troy Duster, Charles Epstein, Ted Friedman, Henry Greely, Leroy Hood, Ruth Hubbard, Sheila Jasanoff, Arthur Kaplan, Daniel Kevles, Mary Clair King, Phillip Kitcher, Julie Korenberg, Michael Malinowski, Desmond Mascarenhas, Pilar Ossario, Gerald Rubin, Lee Silver, and Sylvia Spengler.
The Educational Broadcasting Corporation (WNET in New York) is developing and producing a new public television project exploring cutting-edge technology. The project consists of an eight-part hourly broadcast component; six 60-second "mini-programs;" a World Wide Web component; and extensive educational outreach targeted to adults aged 25-39 and older. The topics for the eight programs in season one are: Replacements - prosthetic devices and biologically electronic artificial body parts In Search of Eve - the race to decode the human genome Light of the 21st Century - Fiber Optics Nanotechnology - molecular manipulation of materials Technospy - technologies used to gain information Sports Technology - the pursuit of better equipment and training regimes Artificial Intelligence - efforts to create computers the mimic human intelligence Appropriate Technologies - technologies that use local, inexpensive material Beth Hoppe, WNET's Director of Science Programs will serve as Executive Producer for the series. Each of the programs would be produced by an independent producer selected by WNET. Content advisors include: Angela Christiano, Departments of Dermatology, Genetics and Development, Columbia University; Sheila Sen Jasanoff, Harvard University JFK School of Government; Horace Freeland Judson, Center for History of Recent Science, George Washington University; Michio Kaku, theoretical physicist, CUNY and host, Explorations radio series; Wilfred Pinfold, Microprocessor Research Labs, Intel Corp.; and Barbara Wilson, chief technologist, NASA's Jet Propulsion Laboratory
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TEAM MEMBERS:
Beth HoppeTamara RobinsonWilliam GrantBarbara Flagg
The Science Museum of Minnesota (SMM) will develop "Cyborgs: A Natural History of Machines and Humans." The Project will result in a national traveling exhibit, a web site, and a complement of related educational programs focused on the boundaries between humans and their machines and on recent scientific efforts to understand the human body and mind. The 6,000-square-foot exhibit will open at the SMM before traveling to the six large museums in the Science Museum Exhibit Collaborative (SMEC), and then will be available for lease by other museums.
The Reuben H. Fleet Space Center is developing "The Search for Infinity," a large-format film on mathematics and nature. The current concept, based on a film idea developed in collaboration with Sir Arthur C. Clarke, is to center the film on an intelligent computer running an unmanned space probe. By following the actions of the computer, audiences will learn about mathematical fractals and the relationships between fractals and the natural world. A key effect planned for the film will be a prolonged zoom into the endless details of the celebrated Mandelbrot Set fractal. Jeffrey Kirsch, Director of the Reuben H. Fleet Space Center, will be PI and Executive Producer for the film. The Co-Executive Producer will be Christina Schmidlin, Vice-President of XAOS, Inc, one of the world's leading computer graphics studios, and the Producer-Director will be Ronald Fricke. This production team will work with Sir Arthur Clarke to write the treatment for the film. Scientists working directly in the pre-production phase of the project include Ian Stewart, Professor of Mathematics at the University of Warwick, and Rudy Rucker of San Jose State University. Other advisors include: Benoit Mandelbrot, Yale University; Maxine Brown, University of Illinois at Chicago; Bernard Pailthorpe, San Diego Supercomputer Center; and David Brin, Science Fiction author and astrophysicist. During this planning phase the project will: (1) identify subjects that are best suited to illustrate the fractal geometry of nature in large format film; (2) conduct front-end evaluation to assess the potential educational benefits of such a film; (3) write a treatment and develop a storyboard for the film; conduct formative evaluation of the treatment; (4) produce a motion picture sequence to demonstrate the educational power of the large format film medium to convey complicated ideas related to computer processes; and (5) develop interactive web-based activity concepts to exploit the film's distribution in the museum-dominated large format film community.
A permanent exhibition entitled "Search for Extraterrestrial Life" will engage visitors at the New York Hall of Science in applying the fundamental biology of life on Earth to understanding the search for life elsewhere. The 4,000 sq. ft. exhibition and accompanying programs will engage visitors in learning more about the wide range of conditions that support life on Earth, and how these life requirements shape the search on Mars and other planetary objects for any existing life forms. In addition, the technologies and strategies that scientists are developing to detect any life elsewhere will be highlighted. It is expected that 500,000 visitors each year will participate with the exhibit and its associated programs. Another dissemination plan for the project will be posting fabrication drawings and scripts in readily accessible formats on the Internet. Copies of all computer interactives on electronic media will be available to science-technology centers, museums and other informal learning institutions.