EdVenture Children's Museum, a hands-on, children's museum in Columbia, S.C., in close collaboration with NIH-funded researchers at the University of South Carolina, proposes a five-year, SEPA project titled "Unlocking the Mysteries of Chronic Diseases: BioInvestigations for Family, School and Youth Audiences." The program will develop teaching laboratories and experiments to educate youth ages 5-14, teens and adults about biomedical science topics in a fun, investigatory way. From these laboratory experiences, EdVenture will also develop educational programs designed to engage disadvantaged audiences in schools and communities to help expose them to the world of science and the benefits of community-based translational research. The laboratories and educational programs will utilize scientific content drawn from NIH-sponsored biomedical research, and will translate the research process and public impact into meaningful experiences for the public. These programs will reach a large population, both urban and rural, in socio-economically depressed areas of the state, promoting students' interest in topics that they may not otherwise be exposed to and encouraging a lifelong familiarity and facility with scientific thought and practice. Throughout the life expectancy of this project, a projected 2.5 million children and adults will experience the laboratories and related educational programs. Long-term goals are to encourage future biomedical science career choices, and most importantly, empower a child to take control over his/her own health decisions and to develop the necessary skills to navigate the flood of health information inherent in the quickly changing landscape that is health today.
The Oregon Museum of Science and Industry (OMSI), in partnership with the J. Craig Venter Institute (JCVI), proposes to develop the Zoo in You: Exploring the Human Microbiome, a 2,000 square foot bilingual (English and Spanish) traveling exhibition for national tour to science centers, health museums, and other relevant venues. The exhibition will engage visitors in the cutting edge research of the National Institutes of Health's (NIH) Human Microbiome Project (HMP) and explore the impact of the microbiome on human health. To enrich the visitor experience, the Zoo in You project will also produce an interactive bilingual website and in-depth programs including science cafes and book groups for adult audiences. JCVI will provide its expertise and experience as a major site for HMP genomics research to the project. In addition, advisors from the Oregon Health & Science University, Multnomah County Library, the Multnomah County Health Department, ScienceWorks Hands-On Museum, Science Museum of Minnesota, and other experts will guide OMSI's development of exhibits and programs. The Institute of Learning Innovation in collaboration with OMSI will evaluate the exhibits, programs, and website. Front-end, formative, remedial, and summative evaluation will be conducted in English and Spanish at OMSI, ScienceWorks, and tour venues. The exhibition's target audience is families and school groups with children in grades 4-12. Latino families are a priority audience and the project deliverables will be developed bilingually and biculturally. The Zoo in You will tour to three venues a year for a minimum of eight years. We conservatively estimate that over two million people will visit the exhibition during the national tour. This project presents a powerful opportunity to inform museum visitors about new discoveries in genomic research, to invite families to learn together, and to present and interpret health-related research findings for diverse audiences. PUBLIC HEALTH RELEVANCE (provided by applicant): Our research education program, the Zoo in You (ZIY): Exploring the Human Microbiome, is relevant to public health because it will inform exhibition visitors and program participants about the significant new research of the NIH's Human Microbiome Project (HMP). Visitors will make connections between basic research, human health, and their own personal experiences. The bilingual (English and Spanish) ZIY exhibits and programs will present research finding and public health information in enjoyable and engaging ways to reach diverse family and adult audiences.
This project brings real scientific research into the public domain by establishing a research laboratory in a museum setting where visitors not only enroll in the study, they help shape it through their work as citizen scientists. Findings from the study will increase the public understanding of how genetic research translates into meaningful personal information that can be used to better understand personal health risks and opportunities. In a community-based participatory research laboratory, school-aged children and their families will participate in an authentic research project on the genetics of taste. In a series of simple but highly specific taste tests, participants will learn which gene variations they possess and how these variations influence how they taste foods. Taste function has been increasingly linked to human health, in that variability in taste sensation correlates with, and may in part be causal for, major health problems, including cardiovascular disease and obesity. Interactive exhibit components will inform participants about the scientific process, the principles of genetics, the human genome project and genetic variation. Teaching the public about their genetic profile and its influence on taste may have a positive impact on major health threats such as cardiovascular disease and obesity. The data collected from museum visitors who choose to enroll in the study will be sent to the museum's academic partners for further analysis and inclusion in their ongoing research analysis and publications. This laboratory experience not only engages and educates the public, but also advances the research enterprise and offers a vivid model for how to translate research into the public domain.
This project will introduce students ages 8-14, including underserved students; their teachers and families; and the general public to three biomedical research areas inspired by NIH's Roadmap for Medical Research: biological pathways, bioinformatics and nanomedicine. These areas are unfamiliar to many adults and are not introduced in science curricula. Using the metaphor of a hardware store (i.e., building materials, tools, parts, home repair projects), the project will introduce families, students and teachers to three ideas: (1) The body maintains and repairs itself at the molecular, cell, tissue, organ and system levels; (2) Biomedical researchers are uncovering new complexities at the molecular level that can increase our understanding of how the body works; and (3) Developments in nanomedicine can lead to discoveries and treatments. In a hardware store theater and workshop space and in a virtual hardware store, the project will develop and present demonstrations and basic- and intermediate-level labs (for 2nd- and 6th-grade students or families); train museum staff and interns to present the programs; offer orientation workshops to teachers from Title I schools; develop a teacher's guide; conduct outreach in middle schools; engage scientists to talk about their work and help them communicate with the public; and create a manual of materials and activities for other science centers. The evaluation plan will include formative research on activities and assessment of how well repair metaphors facilitate understanding of clinical issues. A team of scientists, museum staff, science teachers, and biology and medical students will guide the development of education components.