This award is for a Science and Technology Center devoted to the emerging area of nanobiotechnology that involves a close synthesis of nano-microfabrication and biological systems. The Nanobiotechnology Center (NBTC) features a highly interdisciplinary, close collaboration between life scientists, physical scientists, and engineers from Cornell University, Princeton University, Oregon Health Sciences University, and Wadsworth Center of the New York State Health Department. The integrating vision of the NBTC is that nanobiotechnology will be the genesis of new insights into the function of biological systems, and lead to the design of new classes of nano- and microfabricated devices and systems. Biological systems present a particular challenge in that the diversity of materials and chemical systems for biological applications far exceeds those for silicon-based technology in the integrated-circuit industry. New fabrication processes appropriate for biological materials will require a substantial expansion in knowledge about the interface between organic and inorganic systems. The ability to structure materials and pattern surface chemistry at small dimensions ranging from the molecular to cellular scale are the fundamental technologies on which the research of the NBTC is based. Nanofabrication can also be used to form new analytical probes for interrogating biological systems with unprecedented spatial resolution and sensitivity. Three unifying technology platforms that foster advances in materials, processes, and tools underlie and support the research programs of the NBTC: Molecules of nanobiotechnology; Novel methods of patterning surfaces for attachment of molecules and cells to substrates; and Sensors and devices for nanobiotechnology. Newly developed fabrication capabilities will also be available through the extensive resources of the Cornell Nanofabrication Facility, a site of the NSF National Nanofabrication Users Network. The NBTC will be an integrated part of the educational missions of the participating institutions. NBTC faculty will develop a new cornerstone graduate course in nanobiotechnology featuring nanofabrication with an emphasis on biological applications. Graduate students who enter the NBTC from a background in engineering or biology will cross-train in the other field by engaging in a significant level of complementary course work. Participation in the NBTC will prepare them with the disciplinary depth and cross-disciplinary understanding to become next generation leaders in this emerging field. An undergraduate research experience program with a strong mentoring structure will be established, with emphasis on recruiting women and underrepresented minorities into the program. Educational outreach activities are planned to stimulate the interest of students of all ages. One such activity partnered with the Science center in Ithaca is a traveling exhibition for museum showings on the subject of nano scale size. National and federal laboratories and industrial and other partners will participate in various aspects of the NBTC such as by hosting interns, attendance at symposia and scientist exchanges. Partnering with the industrial affiliates will be emphasized to enhance knowledge transfer and student and postdoctoral training. This specific STC award is managed by the Directorate for Engineering in coordination with the Directorates for Biological Sciences, Mathematical and Physical Sciences, and Education and Human Resources.
This research study involves collaboration between researchers at the University of Maryland, College Park and Bowie State University, an HBCU, to examine a multi-component pre-service model for preparing minority students to teach upper elementary and middle level science. The treatment consists of (1) focused recruitment efforts by the collaborating universities; (2) a pre-service science content course emphasizing inquiry and the mathematics of data management; (3) an internship in an after school program serving minority students; (4) field placements in Prince Georges County minority-serving professional development schools; and (5) mentoring support during the induction year. The research agenda will examine each aspect of the intervention using quantitative and qualitative methods and a small number of case studies.
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TEAM MEMBERS:
James McginnisSpencer BensonScott Dantley
The Nanoscale Science and Engineering Center entitled New England Nanomanufacturing Center for Enabling Tools is a partnership between Northeastern University, the University of Massachusetts Lowell, the University of New Hampshire, and Michigan State University. The NSEC unites 34 investigators from 9 departments. The NSEC is likely to impact solutions to three critical and fundamental technical problems in nanomanufacturing: (1) Control of the assembly of 3D heterogeneous systems, including the alignment, registration, and interconnection at three dimensions and with multiple functionalities, (2) Processing of nanoscale structures in a high-rate/high-volume manner, without compromising the beneficial nanoscale properties, (3) Testing the long-term reliability of nano components, and detect, remove, or prevent defects and contamination. Novel tools and processes will enable high-rate/high-volume bottom-up, precise, parallel assembly of nanoelements (such as carbon nanotubes, nanorods, and proteins) and polymer nanostructures. This Center will contribute a fundamental understanding of the interfacial behavior and forces required to assemble, detach, and transfer nanoelements, required for guided self-assembly at high rates and over large areas. The Center is expected to have broader impacts by bridging the gap between scientific research and the creation of commercial products by established and emerging industries, such as electronic, medical, and automotive. Long-standing ties with industry will also facilitate technology transfer. The Center builds on an already existing network of partnerships among industry, universities, and K-12 teachers and students to deliver the much-needed education in nanomanufacturing, including its environmental, economic, and societal implications, to the current and emerging workforce. The collaboration of a private and two public universities from two states, all within a one hour commute, will lead to a new center model, with extensive interaction and education for students, faculty, and outreach partners. The proposed partnership between NENCET and the Museum of Science (Boston) will foster in the general public the understanding that is required for the acceptance and growth of nanomanufacturing. The Center will study the societal implications of nanotechnology, including conducting environmental assessments of the impact of nanomanufacturing during process development. In addition, the Center will evaluate the economic viability in light of environmental and public health findings, and the ethical and regulatory policy issues related to developmental technology.
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TEAM MEMBERS:
Ahmed BusnainaNicol McGruerGlen MillerCarol BarryJoey Mead
This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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TEAM MEMBERS:
Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
The National Center for Earth-surface Dynamics (NCED) is a Science and Technology Center focused on understanding the processes that shape the Earth's surface, and on communicating that understanding with a broad range of stakeholders. NCED's work will support a larger, community-based effort to develop a suite of quantitative models of the Earth's surface: a Community Sediment Model (CSM). Results of the NCED-CSM collaboration will be used for both short-term prediction of surface response to natural and anthropogenic change and long-term interpretation of how past conditions are recorded in landscapes and sedimentary strata. This will in turn help solve pressing societal problems such as estimation and mitigation of landscape-related risk; responsible management of landscape resources including forests, agricultural, and recreational areas; forecasting landscape response to possible climatic and other changes; and wise development of resources like groundwater and hydrocarbons that are hosted in buried sediments. NCED education and knowledge transfer programs include exhibits and educational programs at the Science Museum of Minnesota, internships and programs for students from tribal colleges and other underrepresented populations, and research opportunities for participants from outside core NCED institutions. The Earth's surface is the dynamic interface among the lithosphere, hydrosphere, biosphere, and atmosphere. It is intimately interwoven with the life that inhabits it. Surface processes span environments ranging from high mountains to the deep ocean and time scales from fractions of a second to millions of years. Because of this range in forms, processes, and scales, the study of surface dynamics has involved many disciplines and approaches. A major goal of NCED is to foster the development of a unified, quantitative science of Earth-surface dynamics that combines efforts in geomorphology, civil engineering, biology, sedimentary geology, oceanography, and geophysics. Our research program has four major themes: (1) landscape evolution, (2) basin evolution, (3) biological sediment dynamics, and (4) integration of morphodynamic processes across environments and scales. Each theme area provides opportunities for exchange of information and ideas with a wide range of stakeholders, including teachers and learners at all levels; researchers, managers, and policy makers in both the commercial and public sectors; and the general public.
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TEAM MEMBERS:
Efi Foufoula-GeorgiouChristopher PaolaGary Parker
The importance of reporting current science to the general public is more important now than ever before. The best way to ensure enthusiastic support for science is to engage the general public as directly as possible. Unlike schooling, learning in a museum is self-motivated, self-directed, and can be lifelong. The partnership between Columbia University's MRSEC (Materials Research Science and Engineering Center) and the New York Hall of Science will do this in an exciting manner by development of innovative 'rolling exhibits' (Discovery Carts) that are visually attractive, intellectually stimulating and demonstrate current research. This project will unite a dynamic University research faculty, dedicated graduate students, and high school teachers from one of the largest and best known teacher research experience programs in the country. NY Hall of Science, specialists in public science education, have developed exhibitions, over the past 20 years, for school and family group visitors in biology, chemistry and physics. Most recently, the Hall opened an 800-foot biochemistry discovery lab featuring ten experiments that teach visitors about the role of molecules in everyday life. The lab is facilitated by an explainer, and hundreds of families use the lab throughout the year. All exhibits and programs have rigorous science presented in an engaging manner in an educationally non-threatening environment. Columbia University is one of the premier research institutions in the country. Columbia's MRSEC is engaged in multi-faceted educational outreach activities in the New York metropolitan area, including a close working relationship with Columbia's 16 year old RET program. Together these institutions are well situated to involve the research community in public education activities that will inform the public about the current advances in science. Teachers and graduate students who have worked in MRSEC labs will assist in bringing new skills and ideas to the development of museum programming and exhibits. The teachers have experienced both the research projects first-hand and have had the experience in translating the research into meaningful classroom activities for their students. The graduate students have worked alongside the teachers, assisting them in making the research meaningful to high school students. Broader Impact: Highly skilled educators who can improve a young person's chances for success are like gold for the nation's schools, which are under pressure for tough accountability standards. Teachers will influence over a thousand students during the course of their careers. The Hall's Explainers are of high school and college age. These two groups will have positive impacts on our society for years to come. They will benefit from participation, and the tens of thousands of visitors to the museum will learn about cutting edge research.
The Center for Informal Learning and Schools (CILS) is a five-year collaborative effort between the Exploratorium in San Francisco, the University of California at Santa Cruz, and King's College London. The purpose of the Center is to study the intersection of informal science learning that takes place in museums and science centers and formal learning that takes place in schools, and to prepare leaders in informal science education. Through the efforts of the center, new doctoral level leaders will be prepared who understand how informal science learning takes place and how informal institutions can contribute to science education reform. A Ph.D. program will be offered to 16 individuals at King's College London (two cohorts of eight) and a post-doctoral program to six scientists interested in issues of learning and teaching in informal settings. A doctoral program is planned at the University of California at Santa Cruz for 24 students, 12 whose interests are primarily in education and 12 who come from the sciences. In addition to doctoral level training, there will be a certification program for existing informal science professionals to better enable them to support teachers, students and the general public. That program will provide 160 informal science educators 120 hours of professional development experiences, and an additional 24 informal science educators with a master's degree in informal science education at UC Santa Cruz. A Bay Area Institute will be developed to serve as a central focus for all CILS activities. It will bring together researchers and practitioners; it will offer courses and workshops for graduate students; and it will provide a central location for reporting research findings and methodologies that focus on how informal learning institutions can best contribute to science education reform.
Building Demand for Math Literacy is a comprehensive project designed to increase arithmetic and algebraic mathematical competency among underserved youth, as well as high school and college students trained as Math Literacy Workers. This project builds on the success of the nationally renowned Algebra Project that is designed to foster mathematics achievement among inner city youth. Math Literacy Workers will deliver after school activities to African-American and Hispanic youth in grades 3-6. In addition to offering weekly math literacy workshops, Math Literacy Workers will also develop and implement Community Events for Mathematics Literacy and activities for families in the following cities: Boston, MA; Chicago, IL; Jackson, MS; Miami, FL; Yuma, AZ; New Orleans, LA; San Francisco, CA and Newark, DE. The strategic impact will be demonstrated in the knowledge gained about the impact of diverse learning environments on mathematics literacy, effective strategies for family support of math learning, and the impact of culturally relevant software. Collaborators include the Algebra Project, the TIZ Media Foundation, and the Illinois Institute of Technology, as well as a host of community-based and educational partners. The project deliverables consist of a corps of trained Math Literacy Workers, workshops for youth, training materials and multimedia learning modules. It is anticipated this project will impact over 4,000 youth in grades 3-6, 700 high school and college students, and almost 4,000 family and community participants.
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TEAM MEMBERS:
Omowale MosesLeroy Kennedy
resourceprojectProfessional Development, Conferences, and Networks
This CAREER grant interweaves research and teaching focused on understanding how social groups construct meaning during scientific conversations across different learning contexts, such as classrooms, museums and the home. This work will be translated into formal educational settings and used to inform teaching practices within pre-service University and in-service school district settings. The research and educational emphasis will be on creating conceptual links between social learning in diverse settings and the creation of corridors of opportunity between formal and informal learning institutions. To date there has been little research with families from cultural and linguistic minority populations, such as Latino families, at informal learning settings and virtually none that integrates formal and informal learning, or impacts teaching. The five-year project will: 1. Conduct Study 1, aimed at making fundamental cross-cultural comparisons of family conversational meaning making at the Monterey Bay Aquarium and linking this work with family interviews, reflective conversations and visits to family homes; 2. Review the theoretical framework and conduct Study 2, which will incorporate lessons learned from Study 1, and linking this research to formal classrooms; and 3. Use the findings (at each stage) to inform teaching practice with UCSC undergraduate (Science majors) and graduate (Science credential, MA and Ph.D.) students, and, in collaboration with teacher research groups for new and experienced teacher in schools that serve predominantly Latino students. This research plan provides an opportunity for viewing several inter-connected mechanisms, including family interactions and conversations, compelling science content, naturalistic learning in museum settings, and, finally, analyzing these factors in order to inform teaching practices that promote bilingual minority students to the rank of scientists.
This project continues the development, testing, and use of a series of web-based computer simulations for improving the teaching and learning of physics. It expands the number of simulations in physics, creates new simulations addressing introductory chemistry, creates simulations addressing the conceptual understanding of equations in solving science problems, and further refines some existing simulations. It increases, by approximately 35, the 35 online interactive simulations that have been developed for teaching physics. The project produces and widely disseminates on-line supporting materials for use in undergraduate and high school science courses. The supporting materials include: guided-discovery, tutorial worksheets; a list of learning goals; materials to support in-lecture, homework, and laboratory use; assessment instruments; and other user-contributed materials. The simulations being introduced and their effectiveness are being evaluated in at least eight additional courses in physics and chemistry at the University of Colorado and a diverse set of partner institutions. The materials are being extensively tested to ensure that they are easy to use and effective at promoting deep conceptual understanding and positive attitudes about science and technology.
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TEAM MEMBERS:
Carl WiemanNoah FinkelsteinKatherine Perkins