The Maryland Science Center (MSC), in collaboration with Johns Hopkins University (JHU), the University of Maryland, Baltimore (UMB), and Morgan State University (MSU), has sought the support of the National Institutes of Health SEPA (Science Education Partnership Award) Program to develop "Cellular Universe: The Promise of Stem Cells," a unique exhibition and update center with related programs that highlight the most current science in cell biology and stem cell research. Visitor surveys have shown that science museum visitors are very interested in learning about stem cell research, but know little about the science of stem cells or cell biology, which form the basis of stem cell research. The goal of this project is to help visitors learn about advances in cell biology and stem cells so that they will make informed health-related decisions, explore new career options, and better understand the role of basic and clinical research in health advances that affect people's lives. Topics to be covered include the basic biology of cells, the role of stem cells in human development, current stem cell research and the clinical research process. This exhibition will also address the controversies in stem cell research. Our varied advisory panel, including cell biologists, physiologists, adult and embryonic stem cell researchers and bioethicists, will ensure the objectivity of all content. "Cellular Universe: The Promise of Stem Cells" will be a 3,500 square-foot exhibition to be planned, designed and prototyped in Fall 2006-Winter 2009, and installed in MSC's second-floor human body exhibition hall in Spring 2009. This exhibition will build on the successful model of "BodyLink," our innovative health science update center funded by a 2000 SEPA grant (R25RR015602) and supported by partnerships with JHU and UMB.
This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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TEAM MEMBERS:
Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
The National Center for Earth-surface Dynamics (NCED) is a Science and Technology Center focused on understanding the processes that shape the Earth's surface, and on communicating that understanding with a broad range of stakeholders. NCED's work will support a larger, community-based effort to develop a suite of quantitative models of the Earth's surface: a Community Sediment Model (CSM). Results of the NCED-CSM collaboration will be used for both short-term prediction of surface response to natural and anthropogenic change and long-term interpretation of how past conditions are recorded in landscapes and sedimentary strata. This will in turn help solve pressing societal problems such as estimation and mitigation of landscape-related risk; responsible management of landscape resources including forests, agricultural, and recreational areas; forecasting landscape response to possible climatic and other changes; and wise development of resources like groundwater and hydrocarbons that are hosted in buried sediments. NCED education and knowledge transfer programs include exhibits and educational programs at the Science Museum of Minnesota, internships and programs for students from tribal colleges and other underrepresented populations, and research opportunities for participants from outside core NCED institutions. The Earth's surface is the dynamic interface among the lithosphere, hydrosphere, biosphere, and atmosphere. It is intimately interwoven with the life that inhabits it. Surface processes span environments ranging from high mountains to the deep ocean and time scales from fractions of a second to millions of years. Because of this range in forms, processes, and scales, the study of surface dynamics has involved many disciplines and approaches. A major goal of NCED is to foster the development of a unified, quantitative science of Earth-surface dynamics that combines efforts in geomorphology, civil engineering, biology, sedimentary geology, oceanography, and geophysics. Our research program has four major themes: (1) landscape evolution, (2) basin evolution, (3) biological sediment dynamics, and (4) integration of morphodynamic processes across environments and scales. Each theme area provides opportunities for exchange of information and ideas with a wide range of stakeholders, including teachers and learners at all levels; researchers, managers, and policy makers in both the commercial and public sectors; and the general public.
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TEAM MEMBERS:
Efi Foufoula-GeorgiouChristopher PaolaGary Parker
resourceprojectProfessional Development, Conferences, and Networks
The Nanoscale Science and Engineering Education (NSEE) Center for Learning and Teaching (NCLT) would focus on the research and development of nano-science instructional resources for grades 7-16, related professional development opportunities for 7-12 teachers, and programs infused with nano-science content for education doctoral students. The Center would bring together educators and scientists from several areas of nano-science and engineering research to collaborate with science teachers and doctoral candidates in education on both the development of the resources and research on their efficacy. The PI has prior experience as director of the Materials World Modules project, an NSF-funded curriculum currently in use in several secondary schools across the country. Lead partners in the proposed Center are Northwestern University, Purdue University, University of Michigan, University of Illinois at Chicago and University of Illinois at Urbana-Champaign. Additional partners include Argonne National Laboratory, West Point Military Academy, Alabama A & M University, Fisk University, Hampton University, Morehouse College and University of Texas at El Paso. The additional partners will widen the geographic range of the project, expanding opportunities to reach a diverse and currently underrepresented population of graduate students, teachers and ultimately students. STEM and Education faculty and researchers from the partner institutions would participate in interdisciplinary teams to address the Center's mission: Provide national education leadership and resources for advancing NSEE Create and implement professional development programs in NSEE Use innovative ideas in learning to design instructional materials for grades 7-16 Conduct research relating to integration of NSEE into science, technology, engineering and mathematics (STEM) education.
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TEAM MEMBERS:
R. P. H. ChangThomas MasonNcholas GiordanoJoseph Krajcik
ScienceQuest is an innovative program created by the Education Development Center that fosters an interest in science and technology among adolescents ages 10-14. This program builds on the successful "ThinkQuest" model, in which small teams of 2-3 students work with adult coaches to research subjects of interest and share their knowledge through the creation of websites. "ScienceQuest" teams focus on science topics and are housed in HUD Neighborhood Network technology centers, located in communities with HUD-assisted or insured housing residents. Participants include individuals with and without disabilities from low-income urban areas. Students select a science topic and research it using online resources, hands-on experiments and visits to museums and science centers. Coaches such as scientists, teachers, museum staff and other role models, as well as on-line scientists, provide assistance by setting goals, devising an action plan and identifying appropriate resources. The "I-Search" model, a four-step strategy used to direct student inquiry, is used to guide investigations and aid in content acquisition. Once completed, websites are mounted on the "ThinkQuest" server. Parental participation is encouraged throughout the process. "ScienceQuest" will be piloted in the greater Boston area in year one, and disseminated to 75 Neighborhood Network sites throughout the country in years two and three of the grant. Each site may have one or more teams. With more than 500 Neighborhood Networks in place, "ScienceQuest" has the potential for widespread dissemination.
Coastal Communities for Science: A Bering Sea Partnership is a 3-year program of collaboration among the WWF-US, four Alaska native rural communities and regional scientists investigating the ecology of the Bering Strait. Its primary purpose is to advance youth interaction with science and it proposes to achieve this by engaging young people from high school and beyond to conduct research with scientists. The project which involves training community youth on science and research methods, capacity building of informal educators in these rural communities to lead and encourage field-based programs, inclusion of community elders in the overall learning and communication of science concepts and the creation of a model of collaboration. The science content, an amalgam of community interest and researcher interest, is grounded in local environmental and economic issues. With WWF's support and electronic technology, this has the potential of being a model project that is broadly disseminated at local, regional and national levels.
Understanding the Science Connected to Technology (USCT) targets information technology (IT) experiences in a comprehensive training program and professional support system for students and teachers in science, technology, engineering and mathematics (STEM). Participants have opportunities to assume leadership roles as citizen volunteers within the context of science and technology in an international watershed basin. Training includes collection, analysis, interpretation and dissemination of scientific data. BROADER IMPACTS: Building on a student volunteer monitoring program called River Watch, the USCT project enables student scientists to conduct surface water quality monitoring activities, analyze data and disseminate results to enhance local decision-making capacity. The project incorporates state and national education standards and has the potential to reach 173 school jurisdictions and 270,000 students. USCT will directly impact 81 teachers, 758 students and 18 citizen volunteers. The USCT project provides direct scientist mentor linkages for each participating school. This linkage provides a lasting process for life-long learning and an understanding of how IT and STEM subject matter is applied by resource professionals. Broader impacts include accredited coursework for teachers and students, specialized training congruent with the "No Child Left Behind Act of 2001," and building partnerships with Native American schools. INTELLECTUAL MERIT: The USCT project is designed to refocus thinking from static content inside a textbook to a process of learning that includes IT and STEM content. The USCT engages students (the next generation of decision makers) in discovery of science and technology and expands education beyond current paradigms and political jurisdictions.
WGBH is producing twelve quarterly television magazine-format programs devoted to the public understanding of current scientific research. The programs will consider the significant areas of on-going research, present the scientists who are conducting the research, portray research as an on-going endeavor and discuss the social impact and ethical implications of major areas of research. Each program will include segments such as the following: Research news update - (5 to 7 mins.) Feature stories about on-going research - 3 (8 to 12 min. each) In-studio discussions following many of the feature stories - ethical, policy and social implications Point/Counterpoint - 2 commentators presenting social, ethical, political and economic aspects of research "Then and Now" segments showing changing nature of scientific research In-studio demonstrations Interstitial moments -- Showcases of interesting and surprising aspects of research Close -- update stories from previous programs, read viewers' input or answer viewers' questions, preview upcoming story. In addition, WGBH will produce three one-hour "Year in Review" programs that report what major research has occurred over the past year and puts it in a context that will help viewers understand the role of current research in all aspects of life. Other major components of the project include on-going collaborations with other Public Understanding of Research Projects, an interactive web site, communication training for scientists to help them explain their work to the public, "Science Cafes" with on-going public programs about cutting-edge research in informal settings, a resource guide for teachers, "Leading Edge" articles in magazines targeted to teens, a "Leading Edge" science contest for students conducted through PBS stations and a station resource kit with information about how to establish local collaborations with researchers, science museums, schools and others.
This comprehensive ITEST project would provide sixty middle and high school teachers with an introduction to Geographic Information System (GIS) and Global Positioning System (GPS) technologies. The project, which brings together a leadership team of educators, science researchers and experts in resource management, is based at the University of Maryland Center for Environmental Science Appalachian Laboratory, a research facility that studies stream and forest ecosystems. The program will focus on environmental applications in which teachers use probes to investigate the properties of local forest and stream ecosystems. Teachers will apply their technology experiences to creating standards based lessons aligned with local curricula. The teacher participants will be recruited from rural, underserved Appalachian communities in western Maryland and northern West Virginia. Local students will be recruited to participate in a four-day summer session that includes field-testing the proposed lessons and learning about career opportunities in information technology.
The MIT Media Laboratory, in collaboration with six museums, will develop the "Playful Invention and Exploration (PIE) Network," with the goal of engaging a broader audience in science inquiry and engineering by enabling more people to create, invent and explore with new digital technologies. PIE museums will integrate the latest MIT technologies and educational research into their ongoing public programs. The museums will organize MindFest events, modeled after a two-day event at MIT in 1999, at which youth, educators, artists, engineers, hobbyists and researchers came together to collaborate on invention projects. The PIE Network will disseminate PIE ideas and activities to educators and families nationally.
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TEAM MEMBERS:
Mitchel ResnickNatalie RuskBakhtiar MikhakMike PetrichKaren Wilkinson
The Ocean Institute will design, develop, evaluate and install "Sea Floor Science," a 5,200 sq. ft. site-wide exhibition designed in partnership with Scripps Institution of Oceanography, the Jet Propulsion Laboratory, and the Institute of Nautical Archaeology at Texas A&M University. "Sea Floor Science" will provide opportunities for families, students and the general public to use authentic oceanographic equipment, tools and technology to recreate a world of ocean research and discovery. Visitors will experience how oceanographers are exploring the largely unknown sea floor to permit better understanding of the origin of sediments and rocks, paleoclimate reconstruction as evidenced by marine microfossils, and the dynamics of oceanic lithospheres and margins. The project is a new approach to museum exhibits. It will test innovative convertibility solutions that enable public areas to serve as both teaching stations and effective exhibits. It will also implement cost-effective update strategies to keep visitors at the forefront of scientific research. "Sea Floor Science" will reach 4,000,000 people in 22 states including on-site and on-line visitors, multi-state teacher networks, videoconferencing participants, science professionals, and replication sites at science centers and aquaria nationally.
Serial Passage: AIDS, Race, and Culture is a multi-part documentary series. The Long-term goals are: 1) to produce a documentary series exploring the specific and devastating impact of H.I.V./AIDS upon Africans and African-Americans; and 2) to create a heightened understanding of the need for H.I.V. prevention among the high-risk group of young, inner-city African-Americans who've so far proved unresponsive to available public health information. Specific Aims: 1) To deconstruct the racial stigma of AIDS, and scientifically confront the conspiracy theories which are firmly linked to the disease in black America, and in Africa; and 2) to work with an inner-city high school science class, actively involving them in the making of the series. Research Design and Methods: 1) To document on film the process of scientific inquiry which led two prominent researchers to their theory on the origin of AIDS; 2) To document on film the social impact of H.I.V/AIDS upon specific African countries, including Uganda and South Africa, and upon African-American communities in the United States; 3) To periodically screen footage of the documentary for the high school class and conduct videotaped discussions between the students and the scientists throughout one academic year; and 4) To give the students a videotaped questionnaire at the beginning and end of the year designed to measure how much they learn about AIDS and its impact upon their particular community.