This award is for a Science and Technology Center devoted to the emerging area of nanobiotechnology that involves a close synthesis of nano-microfabrication and biological systems. The Nanobiotechnology Center (NBTC) features a highly interdisciplinary, close collaboration between life scientists, physical scientists, and engineers from Cornell University, Princeton University, Oregon Health Sciences University, and Wadsworth Center of the New York State Health Department. The integrating vision of the NBTC is that nanobiotechnology will be the genesis of new insights into the function of biological systems, and lead to the design of new classes of nano- and microfabricated devices and systems. Biological systems present a particular challenge in that the diversity of materials and chemical systems for biological applications far exceeds those for silicon-based technology in the integrated-circuit industry. New fabrication processes appropriate for biological materials will require a substantial expansion in knowledge about the interface between organic and inorganic systems. The ability to structure materials and pattern surface chemistry at small dimensions ranging from the molecular to cellular scale are the fundamental technologies on which the research of the NBTC is based. Nanofabrication can also be used to form new analytical probes for interrogating biological systems with unprecedented spatial resolution and sensitivity. Three unifying technology platforms that foster advances in materials, processes, and tools underlie and support the research programs of the NBTC: Molecules of nanobiotechnology; Novel methods of patterning surfaces for attachment of molecules and cells to substrates; and Sensors and devices for nanobiotechnology. Newly developed fabrication capabilities will also be available through the extensive resources of the Cornell Nanofabrication Facility, a site of the NSF National Nanofabrication Users Network. The NBTC will be an integrated part of the educational missions of the participating institutions. NBTC faculty will develop a new cornerstone graduate course in nanobiotechnology featuring nanofabrication with an emphasis on biological applications. Graduate students who enter the NBTC from a background in engineering or biology will cross-train in the other field by engaging in a significant level of complementary course work. Participation in the NBTC will prepare them with the disciplinary depth and cross-disciplinary understanding to become next generation leaders in this emerging field. An undergraduate research experience program with a strong mentoring structure will be established, with emphasis on recruiting women and underrepresented minorities into the program. Educational outreach activities are planned to stimulate the interest of students of all ages. One such activity partnered with the Science center in Ithaca is a traveling exhibition for museum showings on the subject of nano scale size. National and federal laboratories and industrial and other partners will participate in various aspects of the NBTC such as by hosting interns, attendance at symposia and scientist exchanges. Partnering with the industrial affiliates will be emphasized to enhance knowledge transfer and student and postdoctoral training. This specific STC award is managed by the Directorate for Engineering in coordination with the Directorates for Biological Sciences, Mathematical and Physical Sciences, and Education and Human Resources.
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TEAM MEMBERS:
Harold CraigheadBarbara Baird
resourceprojectProfessional Development, Conferences, and Networks
Phylogenetic groupings of organisms are the basis for predictive classifications and biological information systems. Organizing biological knowledge and their parallel hierarchies according to phylogenetic relationships has become increasingly important for many segments of science and society (i.e., genetic databases such as GenBank). Yet, our understanding of the tree of life is still very incomplete at all taxonomic levels because phylogenetic hypotheses are typically characterized by inadequate taxon samples, and the data themselves are often variable across the included taxa with respect to kind, quantity, and quality. In addition, methods of analysis vary in their appropriateness and applicability, thus making comparison of phylogenetic trees difficult. These impediments need to be addressed if we are to have a tree of life for the major groups of organisms within a reasonable time frame. Equally important will be to ensure that phylogenetic knowledge is accessible and useful to researchers, institutions, and the government agencies who need it. This proposal seeks to bring together approximately 25-30 leading systematic biologists and nonsystematists interested in phylogenetic research and informatics (phyloinformatics). The workshop will attempt to identify the research needed to assemble the tree of life and make that information available to the global user community within a reasonable time frame. The workshop will formulate recommendations designed to promote institutional changes within the systematic research community to accelerate phylogenetic understanding, identify research efforts that will result in large-scale increases in phylogenetically informative data and improve data analysis, and specify research, technological advances, and infrastructural needs to store, retrieve, and manipulate large amounts of phylogenetic information and make it widely available.
ScienceQuest is an innovative program created by the Education Development Center that fosters an interest in science and technology among adolescents ages 10-14. This program builds on the successful "ThinkQuest" model, in which small teams of 2-3 students work with adult coaches to research subjects of interest and share their knowledge through the creation of websites. "ScienceQuest" teams focus on science topics and are housed in HUD Neighborhood Network technology centers, located in communities with HUD-assisted or insured housing residents. Participants include individuals with and without disabilities from low-income urban areas. Students select a science topic and research it using online resources, hands-on experiments and visits to museums and science centers. Coaches such as scientists, teachers, museum staff and other role models, as well as on-line scientists, provide assistance by setting goals, devising an action plan and identifying appropriate resources. The "I-Search" model, a four-step strategy used to direct student inquiry, is used to guide investigations and aid in content acquisition. Once completed, websites are mounted on the "ThinkQuest" server. Parental participation is encouraged throughout the process. "ScienceQuest" will be piloted in the greater Boston area in year one, and disseminated to 75 Neighborhood Network sites throughout the country in years two and three of the grant. Each site may have one or more teams. With more than 500 Neighborhood Networks in place, "ScienceQuest" has the potential for widespread dissemination.
MacGillivray Freeman Films is producing a large format film about the exploration and new scientific research aimed at understanding and responding to changes in coral reef ecosystems. The film will examine the complex behavior and interactions among unique Pacific coral reef animals, illustrate the role of scientific research in addressing the declining health of reefs, and stimulate public interest in pursuing further learning and careers in coral reef and marine science. In five coral reef sites the film will feature science researchers who are each a part of the global effort to understand and protect coral reef ecosystems as they document reef diversity and animal behavior, investigate symptoms of reef degradation, provide information on past environmental change through core sampling, and explore life in extreme ocean environments. Outreach materials will include a Museum Resource Guide, Family Fun Sheet, Activities for Informal Education Groups, Teacher Guide and Poster, Web Site/Virtual Field Trip, and Scientist Speaker Series. Greg MacGillivray will be the PI for the project and also will serve as Co-Producer/Co-Director/Co-Director of Photography. Alec Lorimore is Co-Producer and Howard Hall is Co-Director of Photography/Sequence Director/and Cameraman. Science Advisors include: Gerald Allen, Conservation International; Richard Aronson, Dauphin Island Sea Lab and University of South Alabama; Gisele Muller-Parker, Shannon Point Marine Center and Western Washington University; Joseph Levine, WGBH and Discovery Magazine; and Richard Pyle, University of Hawaii and Bishop Museum.
The Science Museum of Minnesota is requesting $279,577, of a total budget of $339,074, to plan and conduct a four-day international conference exploring issues, current practices and future directions related to furthering public understanding of current research in science and technology. The conference will bring together leading museum professionals, scientific researchers, science journalists, television producers, web developers and others who are already engaged in preliminary work for such an effort and who stand to learn from each other's experiences. The conference will center on the role of museums in informing the public about research, but will include representatives from other media and institutions crucial to its success. The specific goals of the conference are to: Explore challenges and barriers that hinder the development of public understanding of research programs. Identify "best practices" and promising models, tools and technologies for presenting current research to the public. Develop partnership strategies for creating public understanding of research program collaborations across the museum, media and research communities. Identify strategies for selecting significant research stories that are relevant to the public. Develop funding strategies and operational approaches that help sustain a consistent public understanding of research effort. The project will be under the direction of David Chittenden, Vice President for Education at the Science Museum of Minnesota. Advisors to the project include: Carol Lynn Alpert, Museum of Science, Boston; John Beatty, Distinguished Teaching Professor, University of Minnesota; Graham Farmelo, Head of Science Communications, Science Museum of London; Richard Hudson, Twin Cities Public Television, St. Paul; Ken Keller, Hubert H. Humphrey Institute of Public Affairs, University of Minnesota; Rob Semper, The Exploratorium; David Ucko, Koshland Science Center and Science Outreach, National Academy of Sciences; and Bonnie VanDorn, Executive Director, Association of Science-Technology Centers.
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TEAM MEMBERS:
David ChittendenAnne HornickelDonald Pohlman
The Fred Friendly Seminars is producing a three-part, prime-time television series about the ethical, legal and social implications of advances in genetic research and technology. The audience for the series is the general public with special emphasis on the scientific and policy-making communities. Each of the programs will begin with a presentation of the basic genetic science linked to a specific ethical and policy issue and then will engage a panel in a Socratic dialogue based on a hypothetical situation related to that issue. The panel will represent a wide range of perspective including scientists, policy makers and people experiencing the dilemmas presenting in the hypothetical situations. Outreach material for the project will be developed by the National Center for Science Literacy, Education and Technology and Exhibition at the American Museum of Natural History. The center will produce a 16-page discussion guide designed for by a variety of informal education organizations that reach the general public. This guide will be available in both print and on the project web site. In addition to the guide, the web site include guidelines about how to use segments of the series as catalysts for discussion, a list of annotated resources on genetics, and a behind-the-scenes look at the genomic research labs of the museum.
EarthTalk Incorporated is producing and distributing 282 "Edge of Discovery" radio programs. Each of the 90-second programs will explore an area of on-going research and will feature "actualities" or recorded voices of scientists explaining their work. The programs will be carried on 700+ public and commercial radio stations. The broadcast programs will be supplemented by an "Edge of Discovery" web presence that will contain the radio programs themselves plus a "More Info" section for each program that includes references to printed articles and links to other web sites on the day's topic as well as supplementary background material such as transcripts of interviews with scientists. The "Edge of Discovery" web page also will feature a "Meet the Scientists" section in which a new scientist will be profiled each month, and it will feature live online "chats" with scientists six times each year. The producers/hosts for the series are Deborah Byrd and Joel Block who created, produced and hosted the highly successful radio series Earth and Sky. The Senior Producer is Marc Airhart who will be primary liaison with the team of researchers and writers. Review of all material developed for the projected will be done by the project's review committee of 95 scientists.
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TEAM MEMBERS:
Deborah ByrdWilliam BrittonMarc AirhartBarbara Flagg
The MIT Media Laboratory, in collaboration with six museums, will develop the "Playful Invention and Exploration (PIE) Network," with the goal of engaging a broader audience in science inquiry and engineering by enabling more people to create, invent and explore with new digital technologies. PIE museums will integrate the latest MIT technologies and educational research into their ongoing public programs. The museums will organize MindFest events, modeled after a two-day event at MIT in 1999, at which youth, educators, artists, engineers, hobbyists and researchers came together to collaborate on invention projects. The PIE Network will disseminate PIE ideas and activities to educators and families nationally.
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TEAM MEMBERS:
Mitchel ResnickNatalie RuskBakhtiar MikhakMike PetrichKaren Wilkinson
Oregon State University will expand its successful Master Science Educators program and create a national model for the delivery of natural science education to elementary and middle school youth. Master Science Educators are volunteers who undergo a rigorous 30-hour training and commit to 50 hours of service to a community site, such as a community center, housing project or school. Volunteers work in teams of two so that each site receives 100 hours of service devoted to the research and development of a natural science project. Volunteers and on-site and off-site scientists who act as virtual volunteers, guide youth ages K-8, in the design, development and evaluation of their project. Wildlife habitat projects provide a means for participants to learn inquiry and are tailored to address local science standards. A trainer's guide, a volunteer handbook, a guide for community sites and promotional and training videos will be produced, as well as a web-based science course. It is anticipated that 240 volunteers will be trained to work with over 12,000 youth during the course of the project. Dissemination will occur through the 4-H Extension service, impacting both urban and rural populations.
The Science Museum of Minnesota (SMM) requests a grant from the National Center for Research Resources through the SEPA program to develop and evaluate a model biomedical science education partnership program in collaboration with the University of Minnesota's Cancer Center, Medical School, School of Public Health, and College of Veterinary Medicine. The museum will work with 19 researchers at the University to develop a multifaceted exhibition and presentation program focusing on the importance of human tissues in biological development, function, and disease. The 1500-square-foot exhibition, to be located in SMM's new Human Body Gallery, will consist of an introduction to tissues and four topical exhibit clusters. Each topic was chosen because it tells a fascinating story of how the human body works and because it represents an important current NIH research focus in health and medicine. The exhibits will emphasize the importance of understanding how tissue function and viability leads to advances in detection, treatment, and curing different diseases. The exhibits closely support the National Science Education Standards Content Standards for Life Science for grades 5-9 (representing the majority of school field trip visitors to the museum.) A complimentary presentation/outreach program will involve NIH-supported researchers in three programs designed to increase public understanding of basic biomedical science, the causes and cures for disease, and the goals and achievements of biomedical research. A Visiting Scientists Program will feature scientists in the museum presenting programs and demonstrations related to their research interests. A Scientist Mentor Program will involve scientists closely with a diverse team of high-school aged youth to develop ongoing demonstrations and community outreach programs. A Dramatic Presentation will bring home to museum visitors the wider ethical and philosophical dimensions of tissue research.
This Phase I SEPA proposal supports a consortium of science and education partners that will develop System Dynamics (SD) computer models to illustrate basic health science concepts. The consortium includes Oregon Health Sciences University (OHSU), Portland Public Schools (PPS), Saturday Academy, and the Portland VA Medical Center. SD is a computer modeling technique in which diagrams illustrate system structure and simulations illustrate system behavior. Desktop computers and commercial software packages allow SD to be applied with considerable success in K-12 education. NSF grants to Portland Public Schools have trained over 225 high school teachers in Portland and surrounding areas. Two magnet programs have been established with an emphasis on systems and at least five other schools offer significant systems curriculum. Major components of this project include (1) Annual summer research internships at OHSU for high school teachers and high school students, (2) Development of SD models relevant to each research project, (3) Ongoing interactions between high school science programs and OHSU research laboratories, (4) Development of curriculum materials to augment the use of the SD model in the high school classroom or laboratory setting, and (5) Development of video materials to support the classroom teacher. Content will focus on four fundamental models: linear input/exponential output, bi-molecular binding (association/dissociation), population dynamics, and homeostasis. Each of these models is very rich and may be extended to a broad variety of research problems. In addition these models may be combined, for example to illustrate the effect of drugs (binding model) on blood pressure (homeostasis model). System Dynamics is an exemplary tool for the development of materials consistent with National Science Education Standards. SD was specifically developed to emphasize interactions among system structure, organization, and behavior. Students use these material as part of inquiry-based science programs in which the teacher serves as a guide and facilitator rather than the primary source of all content information; technical writing by students is also encouraged. Finally, these SD materials will provide a coherent body of work to guide the ongoing professional development of the classroom science teacher.
The Children's Museum of Houston (CMH) and Baylor College of Medicine (BCM) collaborated to create and travel a museum exhibit on children's environmental health for a target audience of children 5-10, their parents, caregivers, and teachers. My Home Planet Earth (MHPE) is based on the NIH-funded, interdisciplinary My Health My World educational program developed at BCM and disseminated nationally through Carolina Biological Supply. The aims of the project are to: (1) expand understanding by children (ages 5-10) and their caregivers of the health consequences of human induced changes in the environment and increase their abilities to make healthful decisions through informal self-directed activities in a museum setting; (2) encourage linkages between formal and informal education settings by providing a model for connecting classroom-based curricula to museum-based exhibits and informal learning programs, based on the My Health My World educational materials and the My Home Planet Earth exhibit and support programs; (3) help parents provide additional environmental health-related informal learning experiences for their children, and promote awareness of science and health careers; and (4) partner scientists and educators in the creation of a model environmental health sciences exhibit and support program for the field of family-centered informal learning. The exhibit and support programs are in the process of touring 18 youth museums, science centers and health museums over six years of travel (2002-2008). An estimated 1.5 million visitors will participate in the project by the end of the tour in 2008. In addition to these visitors, 1,000 families will participate in MHPE Family Learning Events, 9,000 teachers will be introduced to the My Health My World curriculum-360 of whom will participate in a day long MHMW workshop, 36 scientists will partner with host museums to enhance the learning and community impact of the project, and 180,000 children will visit the xhibit during a school field experience.