This is one of three focus point presentations delivered on day one of the Citizen Science Toolkit Conference (at the Cornell Lab of Ornithology in Ithaca, New York on June 20-23, 2007) as part of the opening session titled “Citizen Science Challenges and Opportunities.” Prysby discusses biodiversity inventories and the All Taxa Biodiversity Inventory in Great Smoky Mountains National Park. Prysby uses this case study to illustrate one form of citizen science collaboration as well as how environmental education centers and nature centers can be key partners for citizen science efforts.