The Office for Human Research Protections (OHRP) provides a decision chart as a guide for institutional review boards (IRBs), investigators, and others who decide if an activity is research involving human subjects that must be reviewed by an IRB under the requirements of the U.S. Department of Health and Human Services (HHS) regulations at 45 CFR part 46. OHRP welcomes comment on these decision charts. The charts address decisions on the following: whether an activity is research that must be reviewed by an IRB, whether the review may be performed by expedited procedures, and whether informed
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U.S. Department of Health & Human Services
The Nanoscale Science and Engineering Center entitled New England Nanomanufacturing Center for Enabling Tools is a partnership between Northeastern University, the University of Massachusetts Lowell, the University of New Hampshire, and Michigan State University. The NSEC unites 34 investigators from 9 departments. The NSEC is likely to impact solutions to three critical and fundamental technical problems in nanomanufacturing: (1) Control of the assembly of 3D heterogeneous systems, including the alignment, registration, and interconnection at three dimensions and with multiple functionalities, (2) Processing of nanoscale structures in a high-rate/high-volume manner, without compromising the beneficial nanoscale properties, (3) Testing the long-term reliability of nano components, and detect, remove, or prevent defects and contamination. Novel tools and processes will enable high-rate/high-volume bottom-up, precise, parallel assembly of nanoelements (such as carbon nanotubes, nanorods, and proteins) and polymer nanostructures. This Center will contribute a fundamental understanding of the interfacial behavior and forces required to assemble, detach, and transfer nanoelements, required for guided self-assembly at high rates and over large areas. The Center is expected to have broader impacts by bridging the gap between scientific research and the creation of commercial products by established and emerging industries, such as electronic, medical, and automotive. Long-standing ties with industry will also facilitate technology transfer. The Center builds on an already existing network of partnerships among industry, universities, and K-12 teachers and students to deliver the much-needed education in nanomanufacturing, including its environmental, economic, and societal implications, to the current and emerging workforce. The collaboration of a private and two public universities from two states, all within a one hour commute, will lead to a new center model, with extensive interaction and education for students, faculty, and outreach partners. The proposed partnership between NENCET and the Museum of Science (Boston) will foster in the general public the understanding that is required for the acceptance and growth of nanomanufacturing. The Center will study the societal implications of nanotechnology, including conducting environmental assessments of the impact of nanomanufacturing during process development. In addition, the Center will evaluate the economic viability in light of environmental and public health findings, and the ethical and regulatory policy issues related to developmental technology.
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Ahmed BusnainaNicol McGruerGlen MillerCarol BarryJoey Mead
This collaborative project aims to establish a national computational resource to move the research community much closer to the realization of the goal of the Tree of Life initiative, namely, to reconstruct the evolutionary history of all organisms. This goal is the computational Grand Challenge of evolutionary biology. Current methods are limited to problems several orders of magnitude smaller, and they fail to provide sufficient accuracy at the high end of their range. The planned resource will be designed as an incubator to promote the development of new ideas for this enormously challenging computational task; it will create a forum for experimentalists, computational biologists, and computer scientists to share data, compare methods, and analyze results, thereby speeding up tool development while also sustaining current biological research projects. The resource will be composed of a large computational platform, a collection of interoperable high-performance software for phylogenetic analysis, and a large database of datasets, both real and simulated, and their analyses; it will be accessible through any Web browser by developers, researchers, and educators. The software, freely available in source form, will be usable on scales varying from laptops to high-performance, Grid-enabled, compute engines such as this project's platform, and will be packaged to be compatible with current popular tools. In order to build this resource, this collaborative project will support research programs in phyloinformatics (databases to store multilevel data with detailed annotations and to support complex, tree-oriented queries), in optimization algorithms, Bayesian inference, and symbolic manipulation for phylogeny reconstruction, and in simulation of branching evolution at the genomic level, all within the context of a virtual collaborative center. Biology, and phylogeny in particular, have been almost completely redefined by modern information technology, both in terms of data acquisition and in terms of analysis. Phylogeneticists have formulated specific models and questions that can now be addressed using recent advances in database technology and optimization algorithms. The time is thus exactly right for a close collaboration of biologists and computer scientists to address the IT issues in phylogenetics, many of which call for novel approaches, due to a combination of combinatorial difficulty and overall scale. The project research team includes computer scientists working in databases, algorithm design, algorithm engineering, and high-performance computing, evolutionary biologists and systematists, bioinformaticians, and biostatisticians, with a history of successful collaboration and a record of fundamental contributions, to provide the required breadth and depth. This project will bring together researchers from many areas and foster new types of collaborations and new styles of research in computational biology; moreover, the interaction of algorithms, databases, modeling, and biology will give new impetus and new directions in each area. It will help create the computational infrastructure that the research community will use over the next decades, as more whole genomes are sequenced and enough data are collected to attempt the inference of the Tree of Life. The project will help evolutionary biologists understand the mechanisms of evolution, the relationships among evolution, structure, and function of biomolecules, and a host of other research problems in biology, eventually leading to major progress in ecology, pharmaceutics, forensics, and security. The project will publicize evolution, genomics, and bioinformatics through informal education programs at museum partners of the collaborating institutions. It also will motivate high-school students and college undergraduates to pursue careers in bioinformatics. The project provides an extraordinary opportunity to train students, both undergraduate and graduate, as well as postdoctoral researchers, in one of the most exciting interdisciplinary areas in science. The collaborating institutions serve a large number of underrepresented groups and are committed to increasing their participation in research.
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Tandy WarnowDavid HillisLauren MeyersDaniel MirankerWarren Hunt, Jr.
The "Salmon Research Team: A Native American Technology, Research and Science Career Exposure Program" is a three-year, youth-based ITEST project submitted by the Oregon Museum of Science and Industry. The project seeks to provide advanced information technology and natural science career exposure and training to 180 middle level and high school students. Mostly first-generation college-bound students, the target audience represents the Native American community and those with Native American affiliations in reservation, rural and urban areas. Students will investigate computer modeling of complex ecological, hydrological and geological problems associated with salmon recovery efforts. Field experiences will be provided in three states: Oregon, Washington and northern California. The participation of elders and tribal researchers will serve as a bridge between advanced scientific technology and traditional ecological knowledge to explore sustainable land management strategies. Students will work closely with Native American and other scientists and resource managers throughout the Northwest who use advanced technologies in salmon recovery efforts. Student participation in IT-dependent science enrichment and research activities involving natural science fields of investigation will occur year round. Middle school students are expected to receive at least 330 contact hours including a one-week summer research experience, a one-week spring break program, and seven weekends of residential programs during the school year. The high school component consists of 460 contact hours reflecting one additional week for the summer research experience. In addition to watershed and salmon recovery related research, students will be involved in other ancillary research projects. A vast array of partners are positioned to support the field research experience including, for example, the U.S. Department of the Interior, Redwood National State Park, College of Natural Resources and Sciences at Humboldt State University, Confederated Tribes of the Warm Springs, University of Oregon Institute of Marine Biology, University of Washington Columbia Basin Research project, the Northwest Center for Sustainable Resources at Chemeketa Community College and the Integrated Natural Resource Technology program at Mt. Hood Community College. The project is intended to serve as a model for IT-based youth science programs that address national and state education standards and are relevant to the cultural experience of Native American students. Two mentors will provide continued support to students: an academic mentor at the student's schools and a professional mentor from a local university or natural resource agency. Incentives will be provided for student participation including stipends and internships. Career exposure and work-related skills are integrated throughout the project activities and every program component. Creative strategies are used to encourage family involvement including, for example, salmon bakes and museum discounts.
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Travis Southworth-NeumeyerDaniel Calvert
The National Center for Earth-surface Dynamics (NCED) is a Science and Technology Center focused on understanding the processes that shape the Earth's surface, and on communicating that understanding with a broad range of stakeholders. NCED's work will support a larger, community-based effort to develop a suite of quantitative models of the Earth's surface: a Community Sediment Model (CSM). Results of the NCED-CSM collaboration will be used for both short-term prediction of surface response to natural and anthropogenic change and long-term interpretation of how past conditions are recorded in landscapes and sedimentary strata. This will in turn help solve pressing societal problems such as estimation and mitigation of landscape-related risk; responsible management of landscape resources including forests, agricultural, and recreational areas; forecasting landscape response to possible climatic and other changes; and wise development of resources like groundwater and hydrocarbons that are hosted in buried sediments. NCED education and knowledge transfer programs include exhibits and educational programs at the Science Museum of Minnesota, internships and programs for students from tribal colleges and other underrepresented populations, and research opportunities for participants from outside core NCED institutions. The Earth's surface is the dynamic interface among the lithosphere, hydrosphere, biosphere, and atmosphere. It is intimately interwoven with the life that inhabits it. Surface processes span environments ranging from high mountains to the deep ocean and time scales from fractions of a second to millions of years. Because of this range in forms, processes, and scales, the study of surface dynamics has involved many disciplines and approaches. A major goal of NCED is to foster the development of a unified, quantitative science of Earth-surface dynamics that combines efforts in geomorphology, civil engineering, biology, sedimentary geology, oceanography, and geophysics. Our research program has four major themes: (1) landscape evolution, (2) basin evolution, (3) biological sediment dynamics, and (4) integration of morphodynamic processes across environments and scales. Each theme area provides opportunities for exchange of information and ideas with a wide range of stakeholders, including teachers and learners at all levels; researchers, managers, and policy makers in both the commercial and public sectors; and the general public.
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Efi Foufoula-GeorgiouChristopher PaolaGary Parker
Quarked!™ is a collaborative physics education project at the University of Kansas that provides engaging and educational science experiences for youth ages 7 and up, educators and the general public. This multimedia project material focuses on concepts of scale and matter, and presents subatomic particles as relatable characters in both human and quark or electron form that explore science through story-driven adventures. It includes a comprehensive website with a range of materials including animated videos, games, apps, FAQs and lesson plans, as well as hands-on education programs at the University of Kansas Natural History Museum. Initially, funded through an NSF EPSCoR grant (Grant No. EPS-0236913 and matching support from the State of Kansas through the Kansas Technology Enterprise Corporation and EPP-0354836), this projects continued to grow and new resources have been added through funding from the Kauffman Foundation, Google grants and other NSF awards. Quarked.org attracts more than 75,000 unique visitors annually, local PBS television stations in Kansas and Missouri broadcast the 3D animated videos, and the museum programs have reached more than than 5,000 school participants and continue to be offered.
This paper presents two perspectives that the author believes will contribute to an enhanced ability to describe and understand learning from museums. Arguably, a major strength of the past decade of research on learning from museums has been the description and investigation of many of the myriad factors that appear to influence learning from museums. However, though we now understand the factors, we do not yet know how to consider them holistically. We do not conduct research as if all these variables were important. In addition, we have not sufficiently incorporated scope and scale into our
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Institute for Learning InnovationJohn H Falk
The California Academy of Sciences will develop, evaluate and disseminate exhibits and programs designed to communicate to public audiences the results of research including a biotic inventory of the amphibians and reptiles of Myanmar. Using innovative trading cards for kids, updates to current research exhibits, a poster highlighting research, a pocket guide to venomous snakes of Myanmar and a posting of research -related materials on the CAS website, the project will inform the public about biotic inventory research and conservation in Myanmar. Designed specifically for target audiences of children and adults, the exhibits and programs will serve several hundred thousand CAS visitors annually.
Increasingly, collaboration between business, non-profit, health and educational agencies is being championed as a powerful strategy to achieve a vision otherwise not possible when independent entities work alone. But the definition of collaboration is elusive and it is often difficult for organizations to put collaboration into practice and assess it with certainty. Program evaluators can assist practitioners concerned with the development of a strategic alliance predicated on collaboration by understanding and utilizing principles of collaboration theory. The Strategic Alliance Formative
WNET planned an initiative to involve museums in the outreach associated with Season V of Cyberchase. A written feedback survey gathered information from 32 museums as to their current practices and recommendations with respect to museum kits, discovery carts, discovery boxes, video screenings and educational computer games. The goal of the survey was to assess the needs of the museums and to guide the development of an outreach plan for Season V. Cyberchase is the Emmy Award-winning mathematics series and website on PBS KIDS GO! using broadcast, web, new media and educational outreach to
Overarching evaluation questions focus on continuous improvement, the degree to which the Salmon Camp project achieves it's objectives with regards to students' skills and attitudes, as well as implementation and outcome questions. Evaluation activities are designed to probe five major areas: 1. Student Knowledge and Skills. To what extent do students gain experience with digital tools, field research, and workplace skills? 2. Student Attitudes. How are students' attitudes and self-efficacy as science students changing with involvement in Salmon Camp? How are career interests changing or
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Phyllis AultOregon Museum of Science and Industry
SUMMARY The Peabody Museum at Yale University in New Haven, Connecticut contracted Randi Korn & Associates, Inc. (RK&A) to evaluate the Dinosaurs and More school tour. In the spring of 2004, RK&A surveyed second grade teacher and student samples, including: 27 pre-tour teacher questionnaires, 519 pre-tour student questionnaires, 24 post-tour teacher questionnaires, 412 post-tour student questionnaires. RK&A also conducted 21 teacher and 35 student interviews, and 3 classroom observations to document the impact and effectiveness of the Dinosaurs and More school tour.
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Randi Korn & Associates, Inc.Yale University