The Maryland Science Center (MSC), in collaboration with Johns Hopkins University (JHU), the University of Maryland, Baltimore (UMB), and Morgan State University (MSU), has sought the support of the National Institutes of Health SEPA (Science Education Partnership Award) Program to develop "Cellular Universe: The Promise of Stem Cells," a unique exhibition and update center with related programs that highlight the most current science in cell biology and stem cell research. Visitor surveys have shown that science museum visitors are very interested in learning about stem cell research, but know little about the science of stem cells or cell biology, which form the basis of stem cell research. The goal of this project is to help visitors learn about advances in cell biology and stem cells so that they will make informed health-related decisions, explore new career options, and better understand the role of basic and clinical research in health advances that affect people's lives. Topics to be covered include the basic biology of cells, the role of stem cells in human development, current stem cell research and the clinical research process. This exhibition will also address the controversies in stem cell research. Our varied advisory panel, including cell biologists, physiologists, adult and embryonic stem cell researchers and bioethicists, will ensure the objectivity of all content. "Cellular Universe: The Promise of Stem Cells" will be a 3,500 square-foot exhibition to be planned, designed and prototyped in Fall 2006-Winter 2009, and installed in MSC's second-floor human body exhibition hall in Spring 2009. This exhibition will build on the successful model of "BodyLink," our innovative health science update center funded by a 2000 SEPA grant (R25RR015602) and supported by partnerships with JHU and UMB.
The Oregon Museum of Science and Industry (OMSI), in collaboration with the Small Museum Research Collaborative (SMRC), proposes to create four small bilingual exhibitions in English and Spanish for a national tour to small museums. The exhibitions will focus on current clinical research in nutrition and physical activity and its applications to personal and family wellness. We propose to build four, 700-square-foot traveling exhibitions: two identical exhibitions with a focus on nutrition, and two identical exhibitions with a focus on physical activity. OMSI's SMRC partners bring the experiences and resources of five geographically and thematically diverse small museums to this project. As the lead institution, OMSI brings over 19 years of experience in creating and touring national exhibitions and in collaborative projects with other museums. Front-end, formative, remedial, and summative evaluation will be conducted with family audiences at OMSI and SMRC sites. To extend the visitor experience, OMSI and SMRC will produce related educational materials and programs including a Web site, teachers' guides, small museum staff training, distance-learning programs, and interactive presentations. An SMRC distance-learning network will be created for program dissemination. The project will be developed with the support of local research scientists at the Oregon Health & Science University's (OHSU) General Clinical Research Center (GCRC) and other experts in nutrition and fitness research, health care, and education. The project's audience is family and K-5 school group visitors to small science and children's museums in rural and small urban communities nationwide. Latino families are also a priority audience for the project. Each of the four traveling exhibitions will tour to three venues a year for a minimum of eight years. We conservatively estimate that over two million people will visit the exhibitions during their national tours. This project presents a powerful opportunity to reach museum visitors in rural and underserved communities, to invite families to pursue healthy nutrition and physical activity together, and to present and interpret clinical research findings for diverse audiences.
Serial Passage: AIDS, Race, and Culture. is a 3-4 hour documentary film series and curriculum enhancement that examines the process of scientific inquiry in the development of the serial passage/contaminated needle theory of the origin of HIV/AIDS as well as the disproportionate impact of the pandemic upon Africans and African-Americans. The long term objective of the documentary film series/curriculum enhancement is to foster a heightened awareness of the need for HIV prevention among African-Americans, particularly teenagers, who are at high risk for contracting HIV, and who have often proved unresponsive to traditional HIV prevention messages. African-Americans constitute 12.1 % of the US population but account for almost 50% of the new HIV/AIDS cases. The documentary film series is being made with a small cohort of 20 inner-city African-American high school students in Pittsburgh, Pennsylvania. The students work on the documentary series as footage evaluators, apprentice filmmakers, and will ultimately be its narrative voice. They are also research subjects. An interim evaluation report showed a dramatic increase in the students' perceived knowledge of HIV/AIDS, and a substantial decrease in their reported sexual activity. A widespread and scientifically significant Phase II evaluation of this project would be conducted via pre and post anonymous surveys administered to African-American teenagers, (high school students), and matching control groups. The ABC and PBS networks have already agreed to screen the documentary series for broadcast consideration. The Phase II application proposes to 1) complete editing and postproduction of the documentary series, and 2) work with curriculum writers and an educational video distribution company on the development and dissemination of the documentary series/curriculum enhancement.
Serial Passage: AIDS, Race, and Culture is a multi-part documentary series. The Long-term goals are: 1) to produce a documentary series exploring the specific and devastating impact of H.I.V./AIDS upon Africans and African-Americans; and 2) to create a heightened understanding of the need for H.I.V. prevention among the high-risk group of young, inner-city African-Americans who've so far proved unresponsive to available public health information. Specific Aims: 1) To deconstruct the racial stigma of AIDS, and scientifically confront the conspiracy theories which are firmly linked to the disease in black America, and in Africa; and 2) to work with an inner-city high school science class, actively involving them in the making of the series. Research Design and Methods: 1) To document on film the process of scientific inquiry which led two prominent researchers to their theory on the origin of AIDS; 2) To document on film the social impact of H.I.V/AIDS upon specific African countries, including Uganda and South Africa, and upon African-American communities in the United States; 3) To periodically screen footage of the documentary for the high school class and conduct videotaped discussions between the students and the scientists throughout one academic year; and 4) To give the students a videotaped questionnaire at the beginning and end of the year designed to measure how much they learn about AIDS and its impact upon their particular community.
Goals: 1) Increase the number of Alaskans from educationally and/or economically disadvantaged backgrounds, particularly Alaska Natives, who pursue careers in health sciences and health professions and 2) Inform the Alaskan public about health science research and the clinical trial process so that they are better equipped to make healthier lifestyle choices and better understand the aims and benefits of clinical research. Objectives: 1) Pre-med Summer Enrichment program (U-DOC) at UAA (pipeline into college), 2) Statewide Alaska Student Scientist Corps for U-DOC, 3) students (pipeline into college), 4) Facility-based Student Science Guide program at Imaginarium Science Discovery Center, 5) Job Shadowing/Mentorship Program for U-DOC students and biomedical researchers, 6) Research-based and student-led exhibit, demonstration, and multi-media presentations, 7) Professional Development for educators, 8) North Star Website.
In January 2006, the Dolan DNA Learning Center launched its SEPA Phase I project: Inside Cancer, a media-rich internet site that examines the molecular genetic basis of cancer. We now propose a Phase II Project, which will employ a six-part strategy to broadly disseminate the site and evaluate its use as a resource in high school biology and health education. a) A partnership will disseminate the site to 800 secondary science teachers at one-day workshop held at 20 sites nationwide. This cost-effective program will focus on key concepts and relevant teaching standards, and also provide a dedicated base for conducting second-round training and evaluation activities. b) An online Teacher Center will allow teachers to develop custom multimedia lessons based on Inside Cancer materials. Key features will be a Concept Matrix, Lesson Exchange, and Atomizer, which will match content with teaching standards, facilitate a community approach to lesson plan development, and provide a searchable interface of over 3,000 multimedia content "atoms." c) Fellowships will allow three lead faculty to work directly with DNALC staff to develop the Teacher Center and model lesson plans (DNALC Fellows). Eighty workshop alumni will serve as Regional Fellows and receive stipends to conduct second-round training activities reaching 640 additional teachers. d) An annual review will assess fidelity to project objectives and analyze site logs to detect patterns of use. An online survey of 1,500 Inside Cancer users annually will assess differences in site use among teachers, students, science and medical professionals, and the general public. e) A longitudinal evaluation of 1,440 participants in workshops and second-round activities will gauge how teachers use Inside Cancer and the Teacher Center, and how their teaching behavior changes over time. f) A controlled study will compare attitudinal and learning effects among 280 high school students - half of whom use Inside Cancer in their classes an half who don't. Biology and health classes will be selected from a single school district that reflects the ethnic and racial distribution of the U.S. population.
The Great Lakes Science Center, in collaboration with Case Western Reserve University (CASE), proposes to develop a permanent exhibition and related programs on biomedical engineering. The successful implementation of this project would allow CASE and GLSC to inform a broad constituency about select biomedical research advancements, applied technologies, and their relevance to society. When the project is completed, we will be able to expose many thousands of visitors each year to the updated exhibition - increasing their interest in and understanding of important science concepts underlying advancements in biomedical technology. The exhibition would encompass approximately 2000 square feet and feature approximately 20 exhibits, most of which would be interactive. The major audiences for the exhibition include families, school groups, and general museum visitors. The BioMedTech exhibition is located on the Science Center's main floor, which places an emphasis on the science and technology of particular importance to Northeast Ohio. The exhibition will be accompanied by educational programming, public programs, and wide dissemination around the region and within the Science Center world. When fully implemented, the project could reach many hundreds of thousands of visitors and garner national attention through dissemination efforts. Visitors to the exhibition and participants in related programs will come to a better understanding of the connections between biology and technology while learning of science and engineering's role in improving the quality of life in our society.
The Tech Museum of Innovation and Stanford University School of Medicine Department of Genetics have established longterm partnership to enable the public to draw connections between modern genetics research and choices they face about their health. Together we will develop, produce, evaluate, and disseminate Life's New Frontier, a dynamic exhibition which will inform the public about the goals and methods of modern genetics. Interactive permanent exhibits and guided learning centers, staffed jointly by museum educators and by working scientists (predominantly Stanford graduate students and postdoctoral fellows), will take the public into the minds and laboratories of scientists who are revolutionizing biomedical science. The exhibition and associated public and school programs will emphasize the emerging discipline of bioinformatics, which is fundamental to the Human Genome Project, gene-based diagnosis, rational drug design, and treatment of disease. Life's New Frontier will open in the summer of 2003 to reach an estimated 1.5 million diverse people annually through museum and online visitation. It will set a new standard for the treatment of cutting-edge science in exhibitions by establishing an infrastructure that permits rapid changes to exhibit content, and creating opportunities for visitors to receive personalized science and health updates after their visit. The exhibition also will serve as a platform to foster continuing personal interaction among middle and high school students, Stanford faculty and students, and the general public. The Tech/Stanford partnership will be maintained through staff liaison positions at each partner institution and will be evaluated to assess its effectiveness. We hope to extend this model to other departments at the Stanford University School of Medicine, and to disseminate it as a model for other science center/university partnerships in biomedical sciences. We anticipate significant outcomes of this partnership: the pblic will be better able to apply the ideas of modern genetics to decisions about their health; and a broad range of students from diverse backgrounds will be inspired to pursue biomedical education and research.
1. Build stepwise a prototype -Virtual Clinical Research Center- (VCRC) for K-12 learners and mentors (diverse peers, experts, and patients) by accessing, mobilizing, and linking the human and physical resources of a prototype national network of Clinical Research Centers (CRC) and translational laboratories through state-of-the-art Telemedicine communication and collaborative technologies and featuring T3 or the 3Ts - Teams, Technologies, Translation - of the Clinical Research Enterprise); 2. Develop the Medical Ignorance Exploratorium (MIEx) as a hybrid K-12 cybercafe-health science museum with key features of a) navigable, game-like, 3D environment including -Isles of Medical Ignorance- and -Questionator,- b) Resource Library, c) Live Performance Theater; and d) Collaboration Space, all to stimulate and guide student-centered inquiry about medical breakthroughs, clinical topics, and sick patients (featuring cyber Q3 or the 3Qs-Questions, Questioning, and Questioners); 3. Evaluate the impact and effectiveness of the curricular and delivery resources and models in SA1 and 2 as well as the dissemination in SA4; 4. Disseminate, embed, and expand the refined Virtual CRC and Medical Ignorance Exploratorium in K-12 schools, the clinical research community, and beyond.
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TEAM MEMBERS:
Marlys WitteGrace WagnerMichael Bernas
Children's Hospital Oakland Research Institute (CHORI), in collaboration with the Hall of Health, a hands-on health museum, proposes a two year, Phase II SEPA project entitled Health and Biomedical Science for a Diverse Community. The purpose of this project is to disseminate (1) "Your Genes and Your Choices," a unique, interactive exhibit on social and genetic factors in health, and (2) a 4th and 5th grade health and biomedical science curriculum. The exhibit and curriculum were developed during Phase I. "Your Genes and Your Choices, "which has eight interactive stations and has been piloted at the Hall of Health, is designed for small science museums and health education centers. It will travel to four venues nationwide during Phase II and remain available to other venues after the grant ends. The innovative, activity based curriculum consists of eight instructional units that introduce students to scientific concepts and investigation in the context of the study of diseases and health conditions that disproportionately affect minority populations. The topics are: Fourth Grade: Unit 1: Nutrition: Balance and Imbalance (Obesity); Unit 2. Traumatic Brain Injuries; Unit 3. Infectious Diseases and Immunity; Unit 4. Environmental Toxics: Poisoning Prevention. Fifth Grade: Unit 1. Nutrition: Diabetes; Unit 2. Asthma and Lung Disease; Unit 3. Heart Disease; and Unit 4. Sickle Cell Anemia and Genetics. Each unit consists of five one hour lessons. The curriculum was piloted during Phase I, both in the classroom and in an after school science club, at two elementary schools serving predominantly minority children in Oakland, California. Now we propose to: (1) disseminate the curriculum via science clubs to ten elementary schools in Oakland and Berkeley; (2) offer a series of educator workshops to enhance the skills of teachers and after school personnel to teach scientific investigation and to incorporate the latest findings in biomedical science across the curriculum; and 3) hold family science festivals at each participating school to introduce parents to the topics of the science clubs. The festivals will include hands-on activities, talks by CHORI researchers, and focused discussions with healthcare providers on issues relating to minority health. This project involves clinical as well as basic science investigators, healthcare providers, teachers and health educators, high school and college students, and faculty from San Francisco State University and the University of California at Berkeley. The ultimate goals are to make science interesting and relevant to children who come from ethnically diverse, low income environments; to help them meet state and national objectives for learning in health, science, and scientific inquiry; to help them and their parents understand the relationship between science and health; and to foster their interest in science, so that they may consider future careers related to biomedical science. All project activities will be assessed through formative and summative evaluation. The science clubs will remain in place at the ten participating schools after Phase II funding ends, and the curriculum and evaluation tools will be posted on the internet, and thereby available to others.
Children's Hospital Oakland Research Institute (CHORI), in collaboration with the Hall of Health, a hands-on health museum, proposes a three-year Phase I SEPA project entitled "Health and Biomedical Science for a Diverse Community." The project entails development of a novel, interactive biomedical science curriculum for 4th and 5th grade students in low socioeconomic environments. Complementary to the curriculum, a hands-on exhibit on social and genetic factors in health will be developed to enhance learning by students and families. The curriculum and exhibit will be pilot tested with students from two elementary schools in Oakland, California. The curriculum--which will specifically address minority health issues such as asthma, obesity, diabetes, and heart disease--will include four five-lesson instructional units for 4th grade, and four five-lesson instructional units for 5th grade. In addition to classroom activities, the project will include workshops for teachers, family health and biomedical science nights, field trips to the Hall of Health, and an annual health and biomedical science festival for families. The project will involve clinical as well as basic science investigators, patients and families, and high school and college students. It will draw on the talents of teachers and health educators from the Oakland Unified School District, directors of SEPA projects at the Exploratorium in San Francisco and Lawrence Hall of Science in Berkeley, faculty at San Francisco State University and the University of California at Berkeley, and employees of LeapFrog, Inc., a company located in Emeryville, California, that makes interactive educational products. The ultimate goals of the project are to make science interesting and relevant to children who come from ethnically diverse, low socio-economic environments, to help them and their parents understand the relationship between science and health, and to foster their interest in science so that they may consider future opportunities in careers related to biomedical science. All project activities will undergo front-end, formative, and summative evaluation.
Having developed the concept of near-peer mentorship at the middle school/high school level and utilized it in a summer science education enhancement program now called Gains in the Education of Mathematics and Science or GEMS at the Walter Reed Army Institute of Research (WRAIR), it is now our goal to ultimately expand this program into an extensive, research institute-based source of young, specially selected, near-peer mentors armed with kits, tools, teacher-student developed curricula, enthusiasm, time and talent for science teaching in the urban District of Columbia Public Schools (specific schools) and several more rural disadvantaged schools (Frederick and Howard Counties) in science teaching. We describe this program as a new in-school component, involving science clubs and lunch programs, patterned after our valuable summer science training modules and mentorship program. Our in-house program is at its maximum capacity at the Institute. Near-peer mentors will work in WRAIR's individual laboratories while perfecting/adapting hands-on activities for the new GEMS-X program to be carried out at McKinley Technology HS, Marian Koshland Museum, Roots Charter School and Lincoln Junior HS in DC, West Frederick Middle School, Frederick, MD and Folly Quarter Middle School and Glenelg HS, in Howard County, MD. Based on local demographics in these urban/rural areas, minority and disadvantaged youth, men and women, may choose science, mathematics, engineering and technology (SMET) careers with increasing frequency after participating, at such an early age, in specific learning in the quantitative disciplines. Many of these students take challenging courses within their schools, vastly improve their standardized test scores, take on internship opportunities, are provided recommendations from scientists and medical staff and ultimately are able to enter health professions that were previously unattainable. Relevance to Public Health: The Gains in the Education of Mathematis and Science (GEMS) program educates a diverse student population to benefit their science education and ultimately may improve the likelihood of successfully entry into a health or health-related professions for participating individuals. Medical education has been show to improve public health.