The Nanomedicine Explorer kiosk at the Museum of Science, Boston provides opportunities to learn about nanomedicine, nanotechnology, cancer biology, new research in cancer diagnosis and therapy, and the process of medical research from bench to bedside. This report is the formative evaluation of the prototype of this kiosk, presenting the results of visitor observations, exit surveys, and interviews. The findings of these data served to provide the Nanomedicine Explorer production team a basis from which to make improvements to the program, which was released as Version 1.0 in May of 2009