The Science Cartoon (Sci-Toons) initiative, an informal education program, was developed to engage STEM and non-STEM students and faculty in the creation of science animation. Housed within Brown University’s Science Center, Sci-Toons projects incorporate several students and faculty each semester from both STEM and non-STEM majors. Team members are provided with technical training in animation, storytelling, and scientific concepts. The Sci-Toons model is a new approach for communicating scientific research and concepts to a broad audience via storytelling, animation, high-quality multimedia, and art.